Journal Publications and Book Selections

Publications and book chapters are provided in pdf format and segregated by groups of years.

• 1982-1989
• Soares, M.J. and Talamantes, F. (1982). Placental and serum hormone changes during the second-half of pregnancy in the hamster. Biology of Reproduction 27, 523-529.


• Soares, M.J. and Talamantes, F. (1983). Genetic and litter size effects on serum placental lactogen in the mouse. Biology of Reproduction 29, 165-171.


• Steger, R.W., Bartke, A., Goldman, B.D., Soares, M.J. and Talamantes, F. (1983). Effects of short photoperiod on the ability of golden hamster pituitaries to secrete prolactin and gonadotropins in vitro. Biology of Reproduction 29, 872-878.


• Glasser, S.R., Julian, J., Munir, M.I. and Soares, M.J. (1987). Biological markers during early pregnancy: trophoblastic signals of the periimplantation period. Environmental Health Perspectives 74, 129-147.


• De, M., Hunt, J.S. and Soares, M.J. (1988). Stimulation of rat placental cell DNA synthesis by transferrin. Biology of Reproduction 38, 1123-1128.


• Hunt, J.S., Soares, M.J., Lei, M.-G., Smith, R.N., Wheaton, D., Atherton, R. and Morrison, D.C. (1989). Products of LPS-activated macrophages (TNF-&alpha, TGF-&beta) but not LPS modify DNA synthesis by trophoblast cells exhibiting the 80 KDA LPS-binding protein. Journal of Immunology 143, 1606-1613.


• Deb, S., Youngblood, T., Rawitch, A. and Soares, M.J. (1989). Placental prolactin-like protein-A: identification and characterization of two major glycoprotein species with antipeptide antibodies. Journal of Biological Chemistry 264, 14348-14353.


• Ogle, T.F., Mills, T.M. and Soares, M.J. (1989). Changes in cytosolic and nuclear progesterone receptors during pregnancy in rat placenta. Biology of Reproduction 40, 1012-1019.


• Soares, M.J., De, M., Pinal, C.S. and Hunt, J.S. (1989). Cyclic adenosine- 3',5'-monophosphate analogues modulate rat placental cell growth and differentiation. Biology of Reproduction 40, 435-447.




• 1991-1995
• Faria, T.N., Ogren, L., Talamantes, F., Linzer, D.I.H. and Soares, M.J. (1991). Localization of placental lactogen-I in trophoblast giant cells of the mouse placenta. Biology of Reproduction 44, 327-331.


• Deb, S., Faria, T.N., Roby, K.F., Larsen, D., Kwok, S.C.M., Talamantes, F. and Soares, M.J. (1991). Identification and characterization of a new member of the placental prolactin family: placental lactogen-I variant. Journal of Biological Chemistry 266, 1605-1610.


• Deb, S., Roby, K.F., Faria, T.N., Szpirer, C., Levan, G., Kwok, S.C.M., and Soares, M.J. (1991) Molecular cloning and characterization of prolactin-like protein-C complementary deoxyribonucleic acid. Journal of Biological Chemistry 266, 23027-23032.


• Arbogast, L.A., Soares, M.J., Tomogane, H., and Voogt, J.L. (1992) A trophoblast specific factor(s) suppresses circulating PRL levels and increases tyrosine hydroxylase activity in tuberoinfundibular dopaminergic neurons. Endocrinology 131, 105-113.


• Shida, M.M., Ng, Y.-K., Soares, M.J., Linzer, D.I.H. (1993) Trophoblast-specific transcription from the mouse placental lactogen I gene promoter. Molecular Endocrinology 12, 181-188.


• Deb, S., Hamlin, G.P., Kwok, S.C.M., and Soares, M.J. (1993) Heterologous expression and characterization of prolactin-like protein-A: identification of serum binding proteins. Journal of Biological Chemistry 268, 3298-3305.


• Tomogane H, Arbogast L.A., Soares M.J., Robertson, M., and Voogt, J.L. (1993) A factor(s) from a rat trophoblast cell line inhibits prolactin secretion in vitro and in vivo. Biology of Reproduction 48, 325-332.


• Arbogast, L.A., Soares, M.J., Robertson, M.C., and Voogt, J.L. (1993) A factor(s) from a trophoblast cell line increases tyrosine hydroxylase activity in fetal hypothalamic cell cultures. Endocrinology 133, 111-120.


• Roby, K.F., Deb, S., Gibori, G., Szpirer, C., Levan, G., Kwok, S.C.M., and Soares, M.J. (1993) Decidual prolactin related protein: identification, molecular cloning and characterization. Journal of Biological Chemistry 268, 3136-3142.


• Gu, Y., Soares, M.J., Srivastava, R.K., and Gibori, G. (1994) Expression of decidual prolactin-related protein in the rat decidua. Endocrinology 135, 1422-1427.


• Yamamoto, T., Roby, K.F., Kwok, S.C.M., and Soares, M.J. (1994) Transcriptional activation of cytochrome P450 side chain cleavage enzyme expression during trophoblast cell differentiation. Journal of Biological Chemistry 269, 6517-6523.


• Yamaguchi, M., Ogren, L., Endo, H., Soares, M.J., and Talamantes, F. (1994) Co-localization of placental lactogen-I, placental lactogen-II, and proliferin in the mouse placenta at midpregnancy. Biology of Reproduction 51, 1188-1192.


• Hamlin, G.P., Lu, X.-J., Roby, K.F., and Soares, M.J. (1994) Recapitulation of the pathway for trophoblast giant cell differentiation in vitro: stage-specific expression of members of the prolactin gene family. Endocrinology 134, 2390-2396.


• Hamlin, G.P. and Soares, M.J. (1995) Regulation of DNA synthesis in proliferating and differentiating trophoblast cells: involvement of transferrin, transforming growth factor-&beta, and tyrosine kinases. Endocrinology 136, 322-331.


• Soares, M.J., Chapman, B.M., Kamei, T., and Yamamoto, T. (1995) Control of Trophoblast cell differentiation: lessons from the genetics of early pregnancy loss and trophoblast neoplasia. Development, Growth & Differentiation 37, 355-364.




• 1996-1998
• Rasmussen, C.A., Hashizume, K., Orwig, K.E., Xu, L., and Soares, M.J. (1996) Decidual prolactin-related protein: heterologous expression and characterization. Endocrinology 137, 5558-5566.


• Dai, G., Liu, B., Levan, G., Szpirer, C., Kwok, S.C.M., and Soares, M.J. (1996) Prolactin-like protein-C variant: complementary DNA, unique six exon gene structure, and trophoblast cell-specific expression. Endocrinology 137, 5009-5019.


• Dai, G., Imagawa, W., Liu, B., Levan, G., Szpirer, C., Kwok, S.C.M., and Soares, M.J. (1996) Rcho-1 trophoblast cell placental lactogens: complementary DNAs, heterologous expression, and biological activities. Endocrinology 137, 5020-5027.


• Grümmer, R., Hellmann, P., Traub, O., Soares, M.J., and Winterhager, E. (1996) Regulation of connexin 31 gene expression upon retinoic acid treatment in rat choriocarcinoma cells. Experimental Cell Research 227, 23-32.


• Liu, F., Soares, M.J., and Audus, K.L. (1997) Permeability properties of monolayers of the human trophoblast cell line, BeWo. American Journal of Physiology 273, C1596-C1604.


• Manzella, S.M., Dharmesh, S.M., Cohick, C.B., Soares, M.J., Baenziger, J.U. (1997) Developmental regulation of a pregnancy-specific oligosaccharide structure, NeuAc &alpha 2,6GalNA &beta 1,4GlcNAc on select members of the rat placental prolactin family. Journal of Biological Chemistry 271, 4775-4782.


• Shi, F., Soares, M.J., Avery, M., Liu, F., Zhang, X., and Audus, K.L. (1997) Permeability and metabolic properties of a trophoblast cell line (HRP-1) derived from normal rat placenta. Experimental Cell Research 234, 147-155.


• Rasmussen, C.A., Orwig, K.E., Vellucci, S., and Soares, M.J. (1997) Dual expression of prolactin-related protein in decidua and trophoblast tissues during pregnancy. Biology of Reproduction 55, 647-654.


• Orwig, K.E., Dai, G., Rasmussen, C.A., and Soares, M.J. (1997) Decidual/trophoblast prolactin related protein: characterization of gene structure and cell-specific expression. Endocrinology 138, 2491-2500.


• Orwig, K.E., Ishimura, R., Müller, H., Liu, B., and Soares, M.J. (1997) Identification and characterization of a mouse homolog for decidual/trophoblast prolactin-related protein. Endocrinology 139, 5511-5517.


• Müller, H., Dai, G., and Soares, M.J. (1998) Placental lactogen-I (PL-I) target tissues identified with an alkaline phosphatase-PL-I fusion protein. Journal of Histochemistry & Cytochemistry 46, 737-743.


• Amura, C.R., Kamei, T., Ito, N., Soares, M.J., and Morrison, D.C. (1998) Differential regulation of lipopolysaccharide (LPS) activation pathways in mouse macrophages by LPS binding proteins. Journal of Immunology 161, 2552-2560.


• Dai, G., Chapman, B.M., Liu, B., Wang, D., Orwig, K.E., White, R.A., Preuett, B., and Soares, M.J. (1998) A new mouse member of the prolactin-like protein-C subfamily: structure and expression. Endocrinology 139, 5157-5163


• Das, U.G., Sadiq, F., Soares, M.J., Hay, W.W., and Devaskar, S.U. (1998) Time dependent physiological regulation of rodent and ovine placental glucose transporter (Glut 1) protein. American Journal of Physiology 274, R339-R348.


• Soares, M.J., Dai, G., Orwig, K.E., Peters, T.J., and Müller, H.M. (1998) The uteroplacental prolactin family and pregnancy. Biology of Reproduction 58, 273-284.


• Müller, H., Ishimura, R., Orwig, K.E., Liu, B., and Soares, M.J. (1998) Homologues for prolactin-like protein-A and B are present in the mouse. Biology of Reproduction 58, 45-51.


• 1999-2002
• Peters, T.J., Albieri, A., Bevilaqua, E., Chapman, B.M., Crane, L., Hamlin, G.P., Seiki, M., and Soares, M.J. (1999) Differentiation-dependent expression of gelatinase B/MMP-9 in rat trophoblast cells. Cell & Tissue Research 295, 287-296


• Knipp, G.T., Audus, K.L., and Soares, M.J. (1999) Nutrient transport across the placenta. Advanced Drug Delivery Reviews 38, 41-58


• Dai, G., Chapman, B.M., Wang, D., White, R.A., Preuett, B., and Soares, M.J. (1999) Prolactin-like protein-A gene structure and chromosomal mapping. Mammalian Genome 10, 78-80.


• Müller, H., Liu, B., Croy, B.A., Head, J.R., Hunt, J.S., Dai, G., and Soares, M.J. (1999) Uterine natural killer cells are targets for a trophoblast cell-specific cytokine, prolactin-like protein-A. Endocrinology 140, 2711-2720


• Dai, G., Wolfe, M.W., and Soares, M.J. (1999) Distinct regulatory regions from the prolactin-like protein-C variant promoter direct trophoblast giant cell versus spongiotrophoblast cell-specific expression. Endocrinology 140, 4691-4698


• Orwig, K.E. and Soares, M.J. (1999) Transcriptional activation of the decidual/trophoblast prolactin-related protein gene. Endocrinology 140, 4032-4039


• Knipp, G.T., Liu, B., Audus, K.L., Fujii, H., Ono, T., and Soares, M.J. (2000) Fatty acid transport regulatory proteins in the developing rat placenta and in trophoblast cell culture models. Placenta 21, 367-375


• Peters, T.J. Chapman, B.M., Wolfe, M.W. and Soares, M.J. (2000) Placental lactogen-I gene activation in differentiating trophoblast cells: extrinsic and intrinsic regulation involving mitogen-activated protein kinase signaling pathways. Journal of Endocrinology 165, 443-456


• Bittorf, T., Jaster, R., Soares, M.J., Seiler, J., Brock, J., Friese, K., and Müller, H. (2000) Induction of erythroid proliferation and differentiation by a trophoblast-specific cytokine involves activation of the Jak/STAT pathway. Journal of Molecular Endocrinology 25, 253-262


• Sahgal, N., Knipp, G.T., Liu, B., Chapman, B.M., Dai, G., and Soares, M.J. (2000) Identification of two new nonclassical members of the rat prolactin family. Journal of Molecular Endocrinology 24, 95-108


• Dai, G., Wang, D., Liu, B., Kasik, J.W., Müller, H., White, R.A., Hummel, G.S., and Soares, M.J. (2000) Three novel paralogs of the rodent prolactin gene family. Journal of Endocrinology 166, 63-75


• Wang, D., Ishimura, R., Walia, D.S., Müller, H., Dai, G., Hunt, J.S., Lee, N.A., Lee, J.J., and Soares, M.J. (2000) Eosinophils are cellular targets of the novel uteroplacental heparin-binding cytokine, decidual/trophoblast prolactin-related protein. Journal of Endocrinology 167, 15-29


• Peters, T.J., Chapman, B.M., and Soares, M.J. (2000) Trophoblast differentiation: an in vitro model for trophoblast giant cell development. Methods in Molecular Biology 137, 301-311


• Soares, M.J. and Linzer, D.I.H. (2001) Rodent prolactin family and pregnancy. In: Prolactin, N.D. Horseman (ed), Kluwer Academic Publishers, Norwell, MA , pp. 139-167


• Ain, R., Tash, J.S., and Soares, M.J. (2002) A simple method for the in situ detection of eosinophils. Journal of Immunological Methods 260, 273-278


• Kamei, T., Jones, S.R., Chapman, B.M., McGonigle, K., Dai, G., and Soares, M.J. (2002) The Phosphatidylinositol 3-Kinase/Akt Signaling Pathway Modulates the Endocrine Differentiation of Trophoblast Cells. Molecular Endocrinology 16, 1469-1481


• Dai, G., Lu, L., Tang, S., Peal, M.J., and Soares, M.J. (2002) The prolactin family miniarray: a tool for evaluating uteroplacental/trophoblast endocrine cell phenotypes. Reproduction 124, 755-765


• Audus, K.L., Soares, M.J., and Hunt, J.S. (2002) Characteristics of the fetal/maternal interface with potential usefulness in the development of future immunological and pharmacological strategies. Journal of Pharmacology and Experimental Therapeutics 301, 402-409


• Ain, R., Müller, H., Sahgal, N., Dai, G., and Soares, M.J. (2002) Uteroplacental prolactin family: immunological regulators of viviparity. Neuroimmune Biology 2, 187-202


• 2003-2006
• Wiemers, D.O., Ain R, Ohboshi, S., and Soares, M.J. (2003) Migratory trophoblast cells express a newly identified member of the prolactin gene family. Journal of Endocrinology 179, 335-346


• Wiemers, D.O., Shao, L.-J., Ain, R., Dai, G., and Soares, M.J. (2003) The mouse prolactin gene family locus. Endocrinology 144, 313-325


• Ain, R., Tash, J.S., and Soares, M.J. (2003) Prolactin-like protein-A is a functional modulator of natural killer cells at the maternal-fetal interface. Molecular and Cellular Endocrinology 204, 65-74


• Zhou, F., Tanaka, K., Soares, M.J., and You, G. (2003) Characterization of an organic anion transport system in a placental cell line. American Journal of Physiology 285, E1103-E1109


• Ain, R., Canham, L.N., and Soares, M.J. (2003) Gestation stage-dependent intrauterine trophoblast cell invasion in the rat and mouse: novel endocrine phenotype and regulation. Developmental Biology 260, 176-190


• Soares, M.J. and Wolfe, M.W. (2004) Human embryonic stem cells assemble and fulfill their developmental destiny. Endocrinology 145, 1514-1516


• Ain, R., Trinh, M-L., and Soares, M.J. (2004) Interleukin-11 signaling is required for the differentiation of natural killer cells at the maternal-fetal interface. Developmental Dynamics 231, 700-708


• Thadani, P.V., Strauss, J.F., Dey, S.K., Anderson, V.M., Audus, K.L., Coats, K.S., Cross, J.C., Erlebacher, A., Ganapathy, V., Linzer, D.I., Miller, R.K., Novak, D.A., Rapaka, R.S., Sadovsky, Y., Salafia, C.M., Soares, M.J., and Unadkat, J. (2004) NIDA conference report on placental proteins, drug transport, and fetal development. American Journal of Obstetrics and Gynecology 191, 1858-1862


• Bittorf, T., Jaster, R., Soares, M.J., Seiler, J., Brock, J., Friese, K., and Müller, H. (2000) Induction of erythroid proliferation and differentiation by a trophoblast-specific cytokine involves activation of the Jak/STAT pathway. Journal of Molecular Endocrinology 25, 253-262


• Ain, R., Dai, G., Dunmore, J.H., Godwin, A.R., and Soares, M.J. (2004) A prolactin family paralog regulates reproductive adaptations to a physiological stressor. Proceedings of the National Academy of Sciences U.S.A. 101, 16543-16548


• Soares, M.J. (2004) The prolactin and growth hormone families: pregnancy-specific hormones/cytokines at the maternal-fetal interface. Reproductive Biology & Endocrinology 2, 51 (http://www.rbej.com/content/2/1/51)


• Ain, R. and Soares, M.J. (2004) Is the metrial gland really a gland? Journal of Reproductive Immunology 61, 129-131


• Asano, N., Kondoh, M., Ebiara, C., Fujii, M., Soares, M.J., Nakashima, E., Sato, M., and Watanabe, Y. (2004) Expression profiles of zinc transporters in rodent placental models. Toxicology Letters 154, 45-53


• Arroyo, J.A., Konno, T., Khalili, D., and Soares, M.J. (2005) A simple in vivo approach to investigate invasive trophoblast cells. International Journal of Developmental Biology 49, 977-980


• Rider, V., Potapova, T, Dai, G., and Soares, M.J. (2005) Stimulation of a rat uterine stromal cell line in culture reveals a molecular switch for endocrine-dependent differentiation. Journal of Endocrinology 184, 119-127


• Ain, R., Canham, L.N., and Soares, M.J. (2005) Dexamethasone-induced intrauterine growth restriction impacts the placental prolactin family and the insulin-like growth factor-II/Akt signaling pathway. Journal of Endocrinology 185, 253-263


• Berghorn, K.A., Clark, P.A., Encarnacion, B., DeRegis, C.J., Folger, J., Morasso, M.I., Soares, M.J., Wolfe, M.W., and Roberson, M.S. (2005) Developmental expression of the homeobox protein Distal-less 3 and its relationship to progesterone production in mouse placenta. Journal of Endocrinology 186, 315-323


• Sahgal, N., Canham, L.N., Konno, T., Wolfe, M.W., and Soares, M.J. (2005) Modulation of trophoblast stem cell and giant cell phenotypes: analyses using the Rcho-1 cell model. Differentiation 73, 452-462


• Singh, U., Yu, Y., Kalinina, E., Konno, T., Sun, T., Wakayama, T., Soares, M.J., Hemberger, M., and Fundele, R.H. (2006) Carboxypeptidase E in the mouse placenta. Differentiation 74, 648-660


• Alam, S.M.K., Ain, R., Konno, T., Ho-Chen, J.K., and Soares, M.J. (2006) The rat prolactin gene family locus: species-specific gene family expansion. Mammalian Genome 17, 858-877


• Müller, H. and Soares, M.J. (2006) Alkaline phosphatase fusion proteins as tags for identifying targets for placental ligands. In: Placenta and Trophoblast: Methods and Protocols, Vol 2. M.J. Soares and J.S. Hunt (eds), Humana Press, Totowa, New Jersey, pp. 331-340


• Ho-Chen, J.K., Ain, R., Alt, A., Wood, J.G., Gonzalez, N.C., and Soares, M.J. (2006) Hypobaric-hypoxia as a tool to study pregnancy-dependent responses at the maternal-fetal interface. In: Placenta and Trophoblast: Methods and Protocols, Vol. 2. M.J. Soares and J.S. Hunt (eds), Humana Press, Totowa, New Jersey, pp. 427-434


• Ain, R., Konno, T., Canham, L.N., and Soares, M.J. (2006) Phenotypic analysis of the placenta in the rat. In: Placenta and Trophoblast: Methods and Protocols, Vol. 1. M.J. Soares and J.S. Hunt (eds), Humana Press, Totowa, New Jersey, pp. 295-313


• Soares, M.J., Alam, S.M.K., Konno, T., Ho-Chen, J.K., and Ain, R. (2006) The prolactin gene family and pregnancy-dependent adaptations. Animal Science Journal 77, 1-9


• Sahgal, N., Canham, L.N., Canham, B., and Soares, M.J. (2006) Rcho-1 trophoblast cells: a model for studying trophoblast differentiation. In: Placenta and Trophoblast: Methods and Protocols, Vol. 1. M.J. Soares and J.S. Hunt (eds), Humana Press, Totowa, New Jersey, pp. 159-178


• 2007-2008
• Konno, T., Rempel, L.A., Arroyo, J.A., and Soares, M.J. (2007) Pregnancy in the Brown Norway rat: a model for investigating the genetics of placentation. Biology of Reproduction 76, 709-718


• Ho-Chen, J.K., Bustamante, J.J., and Soares, M.J. (2007) Prolactin-like protein-F subfamily of placental hormones/cytokines: responsiveness to maternal hypoxia. Endocrinology 148, 559-565


• Soares, M.J., Alam, S.M.K., Duckworth, M.L., Horseman, N.D., Konno, T., Linzer, D.I.H., Maltais, L.J., Nilsen-Hamilton, M., Shiota, K., Smith, J.R., and Wallis, M. (2007) A standardized nomenclature for the mouse and rat prolactin superfamilies. Mammalian Genome 18, 154-156


• Alam, S.M.K., Konno, T., Dai, G., Lu, L., Wang, D., Dunmore, J.H., Godwin, A.R., and Soares, M.J. (2007) A uterine decidual cell cytokine ensures pregnancy-dependent adaptations to a physiological stressor. Development 134, 407-415


• Soares, M.J., Konno, T., and Alam, S.M.K. (2007) The prolactin family: effectors of pregnancy-specific adaptations. Trends in Endocrinology and Metabolism 18, 114-121


• Soares, M.J., Alam, S.M.K., Konno, T., and Ain, R. (2007) The prolactin family: regulators of uterine biology. In: Endometrium-2, J. Aplin, A. Fazleabas, S.R. Glasser, L. Giudice (eds), Taylor and Francis Publishers, London, pp. 342-353


• Takahashi, T., Yamada, O., Soares, M.J., and Hashizume, K. (2008) Bovine prolactin-related protein-I is anchored to the extracellular matrix through interactions with type IV collagen. Journal of Endocrinology 196, 225-234


• Rosario, G.X., Konno, T., and Soares, M.J. (2008) Maternal hypoxia-activated endovascular trophoblast cell invasion. Developmental Biology 314, 362-375


• Alam, S.M.K., Konno, T., Sahgal, N., Lu, L., and Soares, M.J. (2008) Decidual cells produce a heparin-binding prolactin family cytokine with putative intrauterine regulatory actions. Journal of Biological Chemistry 283, in press


• Bustamante, J.J., Dai, G., and Soares, M.J. (2008) Pregnancy and lactation modulate maternal splenic growth and development of the erythroid lineage in the rat and mouse. Reproduction, Fertility, and Development 20, 303-310


• Yu, Y., Singh, U., Shi, W., Konno, T., Soares, M.J., Geyer R., and Fundele, R. (2008) Influence of murine maternal hyperglycemia on placental morphology, gene expression, and function. Archives of Physiology and Biochemistry 110, 99-110