Minimum Essential Medium (for 293 cells)

Reagent Final Conc. Volume Mass
MEM (Gibco BRL 61100-061, Sigma #M 0643)     1 bag = 9.5 g
NaHCO3     2.2 g
dH2O   900 mL  

Adjust pH to 7.2. Adjust volume to 1 L. Sterile Filter. Add 10 ml 100x Pen/Strep (Sigma #P 0781) to 1% final concentration.

For culture in less than 5% CO2 (e.g. roller-bottles) add HEPES (SIGMA H-0763) to 20 mM prior to adjustment of pH.

HEPES (MW 260.3) 20 mM   5.2 g

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