Alkaline Phospatase Stain (NBT + BCIP)

Reagent Final Conc. Volume Mass
NBT (nitro blue tetrazolium, FW 817.6), toxic! 0.33 mg/ml   0.0033 g
BCIP (5-bromo-4-chloro-3-indolyl phosphate, FW 370.4) 0.17 mg/ml   0.0017 g
AP buffer 2 (Tris)   10 ml  

 

Reagent Final Conc. Volume Mass
NBT (nitro blue tetrazolium, FW 817.6), toxic! 0.33 mg/ml   0.0165 g
BCIP (5-bromo-4-chloro-3-indolyl phosphate, FW 370.4) 0.17 mg/ml   0.0085 g
AP buffer 2 (Tris)   50 ml  

 

Reagent Final Conc. Volume Mass
NBT (nitro blue tetrazolium, FW 817.6), toxic! 0.33 mg/ml   0.165g
BCIP (5-bromo-4-chloro-3-indolyl phosphate, FW 370.4) 0.17 mg/ml   0.085 g
AP buffer 2 (Tris)   500 ml  

NBT dust is extremely toxic. Store at 4°C. Cover tubes with aluminum foil (both AP substrates are light sensitive).

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