Animal Model for Ovarian Cancer Cell Line

Technology ID: 97KUMC162

Description of Technology: A faculty member has developed ten (10) clonal lines from mouse ovarian surface epithelium of C57B6 mice. 

Injection of these cells intraperitioneally into either nude or syngenic mice induced the formation of bloody ascites with seeding tumors throughout the peritoneal cavity. The mice die within 2-3 months after a single injection. There is no evidence of disease until ascites formation at approximately one (1) week prior to death. In tests for tumorigenicity , all ten (10) cell lines were malignant and produced bloody ascites within 2-5 months. 
We are interested in licensing these cell lines to companies engaged in ovarian cancer research and/or form a collaboration to study the early detection and mouse gene therapy of this disease.

This project was supported by an RO1 grant from the NIH-NCI CA50616

Field of Applications: Ovarian cancer research 

Advantages: 

Stage of Development: NA

Patent Status: NA

Availability: Non-exclusive license. For more information, please contact the Technology
Transfer Office at 913-588-5721.