Michael J. Soares, Ph.D.
University
Distinguished Professor and Vice Chair of Research
Pathology and Laboratory Medicine
Director, Division of Cancer and Developmental Biology
Director, Institute of Maternal-Fetal Biology
Ph.D., University of Hawaii, 1981
Postdoctoral, University of California, Santa Cruz, 1981-1983
Postdoctoral, Baylor College of Medicine, Houston, Texas, 1983-1984
Email: msoares@kumc.edu
Soares Lab web site
Ph.D. students are welcome. Contact
Dr. Soares for more information.
Our laboratory is interested in the regulation of cell differentiation,
especially as related to trophoblast stem cells, and signaling
pathways controlling their developmental fate. We are also interested
in species-specific reproductive adaptations to physiological
stressors and signaling events involved in the establishment
and maintenance of pregnancy; including investigations on the
prolactin gene family, intrauterine inflammatory and immune cells,
uterine vasculature, decidual cells, and the invasive trophoblast
cell lineage. For more information on our research, please
visit the Soares Lab web
site.
Selected Publications
Additional
Publications
- Alam, S.M.K., Ain, R., Konno, T., Ho-Chen, J.K., and Soares,
M.J. (2006) The rat prolactin gene family locus: species-specific
gene family expansion. Mammalian Genome 17, 858-877.
- Alam,
S.M.K., Konno, T., Dai, G., Lu, L., Wang, D., Dunmore, J.H.,
Godwin, A.R., and Soares, M.J. (2007) A uterine decidual cell
cytokine ensures pregnancy-dependent adaptations to a physiological
stressor. Development 134, 407-415.
- Konno, T., Rempel,
L.A., Arroyo, J.A., and Soares, M.J. (2007) Pregnancy in the
Brown Norway rat: a model for investigating
the genetics of placentation. Biology of Reproduction
76, 709-718.
- Soares, M.J., Konno, T., and Alam, S.M.K. (2007)
The prolactin family: effectors of pregnancy-specific
adaptations. Trends
in Endocrinology and Metabolism 18, 114-121.
- Rosario, G.X.,
Konno, T., and Soares, M.J. (2008) Maternal hypoxia-activated
endovascular trophoblast cell invasion. Developmental
Biology 314, 362- 375.
- Alam, S.M.K., Konno, T., Sahgal, N.,
Lu, L., and Soares, M.J. (2008) Decidual cells produce a heparin-binding
prolactin family cytokine with putative intrauterine regulatory
actions. Journal
of Biological Chemistry 283, 18957-18968.