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Department of Pathology and Laboratory Medicine
Pathology and Laboratory Medicine  :  Faculty

Faculty


Dave Pinson

David M. Pinson, DVM, PhD

dpinson@kumc.edu
(913) 588-7351
University of Kansas Medical Center
Mail Stop 1031
3901 Rainbow Boulevard
Kansas City, KS 66160

Research Interests are in immunobiology, AIDS research, and infectious disease.

Academic Positions

  • Director, Lab Animal Resources
  • Clinical Professor

Recent Publications

  • Dhillon, NK, Sui Y, Potula R, Dhillon S, Adany I, Li Z, Villinger F, Pinson D, Narayan O, Buch, S.  Inhibition of pathogenic SHIV replication in macaques treated with antisense DNA of interleukin-4.  Blood 105:  3094-3099, 2005.
  • Sui Y, Li S, Pinson D, Adany I, Li Z, Villinger F, Narayan O, Buch S.  Simian human immunodeficiency virus-associated pneumonia correlates with increased expression of MCP-1, CXCL10, and viral RNA in the lungs of rhesus macaques.  American J Pathology 166:  355-365, 2005.
  • Rozman KK, Lebofsky M, Pinson DM.  Chronic toxicity and carcinogenicity of 1,2,3,4,6,7,8-heptachlorodibenzo-dioxin displays a distinct dose/time toxicity threshold (cxt=k) and a life-prolonging subthreshold effect.  Food Chem Toxicol 43:  729-740, 2005.
  • Vanden Heuvel GB, Brantley JG, Alcalay NI, Sharma M, Kemeny G, Warolin J, Ledford AW, Pinson DM.  Hepatomegaly in transgenic mice expressing the homeobox gene Cux-1.  Mol Carcinog 43:  18-30, 2005.
  • Smith MS, Niu Y, Buch S, Li Z, Adany I, Pinson DM, Potula R, Novembre FJ, Narayan O.  Active simian immunodeficiency virus (strain smmPGm) infection in macaque central nervous system correlates with neurologic disease.  J Acquir Immune Defic Syndr  38:  518-530, 2005.
  • Culley NC, Pinson DM, Chakrabarty A, Mayo MS, LeVine SM.  Pathophysiological manifestations in mice exposed to anthrax lethal toxin.  Infection and Immunity 73:  7006-7010, 2005.
  • Saghir SA, Lebofsky M, Pinson DM, Rozman KK.  Validation of Haber’s rule (dose x time = constant) in rats and mice for monochloroacetic acid and 2,3,7,8- tetrachlorobebenzo-p-dioxin under conditions of kinetic steady state.  Toxicology 215:  48-56, 2005.
  • Sui Y, Stehno-Bittel L, Li S, Loganathan R, Dhillon NK, Pinson D, Nath A, Kolson D, Narayan O, Buch S.  CXCL10-induced cell death in neurons: role of calcium dysregulation.  Eur J Neurosci. 2006 Feb;23(4):957-64.
  • Gaedigk R, Law DJ, Fitzgerald-Gustafson KM, McNulty SG, Nsumu NN, Modrcin AC, Rinaldi RJ, Pinson D, Fowler SC, Bilgen M, Burns J, Hauschka SD, White RA.   Improvement in survival and muscle function in an mdx/utrn(-/-) double mutant mouse using a human retinal dystrophin transgene.  Neuromuscul Disord. 2006 Mar;16(3):192-203.
  • Hout DR, Gomez ML, Pacyniak E, Gomez LM, Fegley B, Mulcahy ER, Hill MS, Culley N, Pinson DM, Nothnick W, Powers MF, Wong SW, Stephens EB.   Substitution of the transmembrane domain of Vpu in simian-human immunodeficiency virus (SHIVKU1bMC33) with that of M2 of influenza A results in a virus that is sensitive to inhibitors of the M2 ion channel and is pathogenic for pig-tailed macaques.
    Virology. 2006 Jan 20;344(2):541-59

Honors, awards, special credentials and/or special skills

  • Veterinary anatomic pathology

Advisory boards, National committees

  • Editorial Board, Vaccine Immunology