Skip redundant pieces
Office of Cultural Enhancement & Diversity

Science References and Research Tools

ENTREZ
Entrez is the text-based search and retrieval system used at NCBI for the major databases, including PubMed, Nucleotide and Protein Sequences, Protein Structures, Complete Genomes, Taxonomy, and others. 

MAP VIEWER
The Map Viewer supports search and display of genomic information by chromosomal position. Retrieve informantion by text queries (e.g. gene or marker name) or by sequence alignment (BLAST). Results display whole genome levels allowing for selected details to display. Multiple display configurations are controlled by the searcher, allowing data downloading, navigation paths to related data. Tools for analysis of information  provided.

CHIME DOWNLOAD

Other Structure Viewer

BLAST
BLAST provides sequence alignments a powerful way to compare novel sequences with previously characterized genes. Functional and evolutionary information can be inferred from well designed queries and alignments. BLAST 2.0, (Basic Local Alignment Search Tool), provides a method for rapid searching of nucleotide and protein databases. Since the BLAST algorithm detects local as well as global alignments, regions of similarity embedded in otherwise unrelated proteins can be detected. Both types of similarity may provide important clues to the function of uncharacterized proteins.

NUCLEOTIDES
The Entrez Nucleotides database is a collection of sequences from several sources, including GenBank, RefSeq, and PDB. The number of bases grows at an exponential rate.

RefSeq
The Reference Sequence collection aims to provide a comprehensive, integrated, non-redundant set of sequences, including genomic DNA, transcript (RNA), and protein products, for major research organisms.

CGAP
The Cancer Genome Anatomy Project (CGAP) is an interdisciplinary program established and administered by the National Cancer Institute (NCI) to generate the information and technological tools needed to decipher the molecular anatomy of the cancer cell. 

dictyBase Genome Browser
Dictyostelium discoideum is a powerful system for basic biomedical research in cell and developmental biology. The organism has unique advantages for studying fundamental cellular processes such as cytokinesis, motility, phagocytosis, chemotaxis, signal transduction and aspects of development such as cell sorting, pattern formation, and cell-type determination.with powerful molecular genetic tools. 

PROTEIN SEQUENCE
The protein entries in the Entrez search and retrieval system have been compiled from a variety of sources, including SwissProt, PIR, PRF, PDB, and translations from annotated coding regions in GenBank and RefSeq.

GENOME
The whole genomes of over 1000 viruses and over 100 microbes can be found in Entrez Genome. The genomes represent both completely sequenced organisms and those for which sequencing is in progress. All three main domains of life - bacteria, archaea, and eukaryota - are represented, as well as many viruses and organelles.

STRUCTURES
Cn3D is a helper application for your web browser that allows you to view 3-dimensional structures from NCBI's  Entrez retrieval service. Cn3D runs on Windows, Macintosh, and Unix. Cn3D simultaneously displays structure, sequence, and alignment, and now has powerful annotation and alignment editing features.  DOWNLOAD SITE.

NCBI Entrez Taxonomy
The NCBI taxonomy database contains the names of all organisms that are represented in the genetic databases with at least one nucleotide or protein sequence. Click on the tree if you want to browse the taxonomic structure or retrieve sequence data for a particular group of organisms.