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"Umbilical Cord Stem Cells", Stem Cells in Endocrinology, Humana Press.
Papagerakis S, Rowe PSN, MacDougall M
MEPE expression pattern in craniofacial mineralized tissues.
J Dent Res: Submitted 2005
Song LH, Pan W, Yu YH, Quarles LD, Zhou HH, Xiao ZS.
Resveratrol prevents CsA inhibition of proliferation and
osteoblastic differentiation of mouse bone marrow-derived mesenchymal stem cells through an ER/NO/cGMP pathway.
Toxicol In Vitro. 2006 Sep;20(6):915-22. Epub 2006 Mar 9.
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Kang JS, Wang XP, Miner JH, Morello R, Sado Y, Abrahamson DR, Borza DB.
Loss of alpha3/alpha4(IV) collagen from the glomerular basement membrane induces a strain-dependent isoform switch to alpha5alpha6(IV) collagen associated with longer renal
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J Am Soc Nephrol. 2006 Jul;17(7):1962-9. Epub 2006 Jun 12.
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Vanden Heuvel GB, Payne JA, Igarashi P, Forbush B 3rd.
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Gene Expr Patterns. 2006 Jun 28; [Epub ahead of print]
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Liu S, Tang W, Zhou J, Stubbs JR, Luo Q, Pi M, Quarles LD.
Fibroblast growth factor 23 is a counter-regulatory
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J Am Soc Nephrol. 2006 May;17(5):1305-15. Epub 2006 Apr 5.
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Am J Physiol Endocrinol Metab. 2006 Jul;291(1):E38-49. Epub 2006 Jan 31.
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J Am Soc Nephrol.2006 Jun;17(6):1498-500. Epub 2006 May 10. No abstract available.
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Salinardi, B., J.K. Roush, T. Schermerhorn, and K.E. Mitchell, (2006)
Matrix Metalloproteinase, Tissue Inhibitors, and Interferon-alpha in Synovial Fluid and Serum of Dogs,
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J Am Soc Nephrol. 2006 Jan;17(1):178-87. Epub 2005 Nov 30.
PMID: 16319189
Thummel R, Bai S, Sarras MP Jr, Song P, McDermott J, Brewer J, Perry M, Zhang X, Hyde DR, Godwin AR.
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Dev Dyn. 2006 Feb;235(2):336-46.
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J Am Soc Nephrol. 2006 Jan;17(1):12-4. Epub 2005 Dec 7. No abstract available.
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Sonographic assessment of the severity and progression of autosomal dominant
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Pi M, Faber P, Ekema G, Jackson PD, Ting A, Wang N,
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Wagoner K, Sanchez G, Nguyen AN, Enders GC, Blanco G.
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Reproduction. 2005 Nov;130(5):627-41.
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Hjelmeland AB, Schilling SH, Guo X, Quarles D, Wang XF.
Loss of Smad3-mediated negative regulation of Runx2 activity leads to an
alteration in cell fate determination.
Mol Cell Biol. 2005
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Semin Nephrol. 2005 Sep;25(5):292-303. Review.
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Sharma D, Holets L, Zhang X, Kinsey WH. (2005)
Role of Fyn kinase in signaling associated with epiboly during zebrafish development.
Dev Biol. 2005 Sep 15; 285(2):462-76.
Pi M, Quarles LD.
Osteoblast calcium-sensing receptor has characteristics of ANF/7TM receptors.
J Cell Biochem. 2005 Aug 15;95(6):1081-92.
Xiao Z, Awad HA, Liu S, Mahlios J, Zhang S, Guilak F, Mayo MS, Quarles LD.
Selective Runx2-II deficiency leads to low-turnover osteopenia in adult mice.
Dev Biol. 2005 Jul 15;283(2):345-56.
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Quarles LD.
Cinacalcet HCl: a novel treatment for secondary hyperparathyroidism in stage 5
chronic kidney disease.
Kidney Int Suppl. 2005 Jul;(96):S24-8.
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Liu S, Brown TA, Zhou J, Xiao ZS, Awad H, Guilak F, Quarles LD.
Role of matrix extracellular phosphoglycoprotein in the pathogenesis of X-linked
hypophosphatemia.
J Am Soc Nephrol. 2005 Jun;16(6):1645-53. Epub 2005 Apr 20.
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Polycystin-2 accelerates Ca(2+) release from intracellular stores in Caenorhabditis elegans.
Cell Calcium. 2005 Jun;37(6):593-601. Epub 2005 Apr 14.
Steenhard BM, Isom KS, Cazcarro P, Dunmore JH, Godwin AR, St John PL, Abrahamson DR.
Integration of Embryonic Stem Cells in Metanephric Kidney Organ Culture.
J Am Soc Nephrol. 2005 Jun;16(6):1623-31.
Vanden Heuvel GB, Brantley JG, Alcalay NI, Sharma M, Kemeny G, Warolin J, Ledford AW, Pinson DM.
Hepatomegaly in transgenic mice expressing the homeobox gene Cux-1.
Mol Carcinog. 2005 May;43(1):18-30.
Pi M, Oakley RH, Gesty-Palmer D, Cruickshank RD, Spurney RF, Luttrell LM,
Quarles LD.
Beta-arrestin- and G protein receptor kinase-mediated calcium-sensing receptor
desensitization.
Mol Endocrinol. 2005 Apr;19(4):1078-87. Epub 2005 Jan 6.
Pi, M., Oakley, R., Cruickshank, R.D., Spurney, R.F., Quarles, L.D.:
GRK2 and 4 Mediates desensitization of CASR
by different mechanisms. (Submitted).
Wang L, Liu S, Quarles LD, Spurney RF.
Targeted overexpression of G protein-coupled receptor kinase-2 in osteoblasts
promotes bone loss.
Am J Physiol Endocrinol Metab. 2005 Apr;288(4):E826-34. Epub 2004 Dec 7.
Moe SM, Chertow GM, Coburn JW, Quarles LD, Goodman WG, Block GA, Drueke TB,
Cunningham J, Sherrard DJ, McCary LC, Olson KA, Turner SA, Martin KJ.
Achieving NKF-K/DOQI bone metabolism and disease treatment goals with cinacalcet
HCl.
Kidney Int. 2005 Feb;67(2):760-71.
Pan W, Quarles LD, Song LH, Yu YH, Jiao C, Tang HB, Jiang CH, Deng HW, Li YJ, Zhou HH, Xiao ZS.
Genistein stimulates the osteoblastic differentiation via NO/cGMP in bone marrow culture.
J Cell Biochem. 2005 Feb 1;94(2):307-16.
Sharma M, Brantley JG, Alcalay NI, Zhou J, Heystek E, Maser RL, Vanden Heuvel GB.
Differential expression of Cux-1 and p21 in polycystic kidneys from Pkd1 null and cpk mice.
Kidney Int. 2005 Feb;67(2):432-42.
Rowe PS, Garrett IR, Schwarz PM, Carnes DL, Lafer EM, Mundy GR, Gutierrez GE.
Surface plasmon resonance (SPR) confirms that MEPE binds to PHEX via the MEPE-ASARM motif: a model for impaired mineralization in X-linked rickets (HYP).
Bone. 2005 Jan;36(1):33-46. Epub 2004 Nov 24.
PMID: 15664000 [PubMed - indexed for MEDLINE]
Rowe PS, Garrett IR, Schwarz PM, Carnes DL, Lafer EM, Mundy GR, Gutierrez GE.
Surface plasmon resonance (SPR) confirms that MEPE binds to PHEX via the
MEPE-ASARM motif: a model for impaired mineralization in X-linked rickets (HYP).
Bone. 2005 Jan;36(1):33-46. Epub 2004 Nov 24.
PMID: 15664000 [PubMed - indexed for MEDLINE]
Tsai WB, Zhang X, Sharma D, Wu W, Kinsey WH.
(2005) Role of Yes kinase during early zebrafish development.
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Responses of pulmonary platelet-derived growth factor peptides and receptors to hyperoxia and nitric oxide in piglet lungs.
Pediatr Res. 57(4):523-9.
Bresler D, Bruder J, Mohnike K, Fraser WD, Rowe PS.
Serum MEPE-ASARM-peptides are elevated in X-linked rickets (HYP): implications for phosphaturia and rickets.
J Endocrinol. 2004 Dec;183(3):R1-9.
PMID: 15590969 [PubMed - indexed for MEDLINE]
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Coexpression of Cux-1 and Notch signaling pathway components during kidney development.
Dev Dyn. 2004 Dec;231(4):828-38.
Bresler D, Bruder J, Mohnike K, Fraser WD, Rowe PS.
Serum MEPE-ASARM-peptides are elevated in X-linked rickets (HYP): implications for phosphaturia and rickets.
J Endocrinol. 2004 Dec;183(3):R1-9.
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Polycystin-1 activates the calcineurin/NFAT (nuclear factor of activated T-cells) signaling pathway.
J Biol Chem. 2004 Dec 31;279(53):55455-64. Epub 2004 Oct 5.
Nichols MT, Gidey E, Matzakos T, Dahl R, Stiegmann G, Shah
RJ, Grantham JJ, Fitz JG, Doctor RB.
Secretion of cytokines and growth factors into autosomal dominant polycystic kidney disease liver cyst fluid.
Hepatology. 2004 Oct;40(4):836-46.
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Freeburg PB, Abrahamson DR.
Divergent expression patterns for hypoxia-inducible factor-1beta and aryl hydrocarbon
receptor nuclear transporter-2 in developing kidney.
J Am Soc Nephrol. 2004 Oct;15(10):2569-78.
Thummel R, Li L, Tanase C, Sarras MP Jr, Godwin AR. Related Articles, Links
Differences in expression pattern and function between zebrafish hoxc13
orthologs: recruitment of Hoxc13b into an early embryonic role.
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Rowe PS.
The wrickkened pathways of FGF23, MEPE and PHEX.
Crit Rev Oral Biol Med. 2004 Sep 1;15(5):264-81. Review.
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Cyclic AMP promotes growth and secretion in human polycystic kidney epithelial cells.
Kidney Int. 2004 Sep;66(3):964-73.
Malizos KN, Quarles LD, Dailiana ZH, Rizk WS, Seaber AV, Urbaniak JR.
Analysis of failures after vascularized fibular grafting in femoral head necrosis.
Orthop Clin North Am. 2004 Jul;35(3):305-14, viii.
Wang L, Quarles LD, Spurney RF. Related Articles, Links
Unmasking the osteoinductive effects of a G-protein-coupled receptor (GPCR) kinase (GRK) inhibitor by treatment with PTH(1-34).
J Bone Miner Res. 2004 Oct;19(10):1661-70. Epub 2004 Jul 14.
Yamaguchi T, Wallace DP, Magenheimer BS, Hempson SJ, Grantham JJ, Calvet JP. Related Articles, Links
Calcium restriction allows cAMP activation of the B-Raf/ERK pathway, switching cells to a cAMP-dependent growth-stimulated phenotype.
J Biol Chem. 2004 Sep 24;279(39):40419-30. Epub 2004 Jul 19.
Wallace DP, Reif G, Hedge AM, Thrasher JB, Pietrow P. Related Articles, Links
Adrenergic regulation of salt and fluid secretion in human medullary collecting duct cells.
Am J Physiol Renal Physiol. 2004 Oct;287(4):F639-48. Epub 2004 Jun 29.
Xiao ZS, Hjelmeland AB, Quarles LD.
Selective deficiency of the "bone-related" Runx2-II unexpectedly preserves
osteoblast-mediated skeletogenesis.
J Biol Chem. 2004 May 7;279(19):20307-13. Epub 2004 Mar 7.
Pi, M., Quarles, L.D.:
The novel cation-sensing mechanism in osteoblasts is a molecular target for strontium.
J Bone Miner Res 2004 May;19(5):862-9. Epub 2004 Jan 12.
Venglarik CJ, Gao Z, Lu X.
Evolutionary conservation of Drosophila polycystin-2 as a calcium-activated cation channel.
J Am Soc Nephrol. 2004 May;15(5):1168-77.
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Gao Z, Joseph E, Ruden DM, Lu X.
Drosophila Pkd2 is haploid-insufficient for mediating optimal smooth muscle contractility.
J Biol Chem. 2004 Apr 2;279(14):14225-31. Epub 2004 Jan 19.
PMID: 14732716 [PubMed - indexed for MEDLINE]
Freeburg PB, Abrahamson DR
Dissecting the JGA: new functions for JG cells?
Am J Physiol Regul Integr Comp Physiol. 2004 Mar;286(3):R449-50
Rowe PS, Kumagai Y, Gutierrez G, Garrett IR, Blacher R, Rosen D, Cundy J,Navvab S, Chen D, Drezner MK, Quarles LD, Mundy GR.
MEPE has the properties of an osteoblastic phosphatonin and minhibin.
Bone. Feb 2004 34(2):303-19, 2004.
Nims N, Vassmer D, Maser RL
Transmembrane domain analysis of polycystin-1, the product of the polycystic kidney disease-1 (PKD1) gene: evidence for 11 membrane-spanning domains.
Biochemistry. 2003 Nov 11;42(44):13035-48.
Freeburg PB, Abrahamson DR.
Hypoxia-inducible factors and kidney vascular development.
J Am Soc Nephrol. 2003 Nov;14(11):2723-30.
Grantham JJ. Lillian Jean Kaplan
International Prize for advancement in the understanding of polycystic kidney
disease. Understanding polycystic kidney disease: a systems biology approach.
Kidney Int. 2003 Oct, 64(4):1157-62.
Zheng D, Wolfe M, Cowley BD Jr, Wallace DP, Yamaguchi T, Grantham JJ.
Urinary excretion of monocyte chemoattractant protein-1 in autosomal dominant polycystic kidney disease.
J Am Soc Nephrol. 2003 Oct, 14 (10): 2588-95.
Maser RL, Magenheimer BS, Zien CA, Calvet JP.
Transient transfection assays for analysis of signal transduction in renal cells.
Methods Mol Med. 2003;86:205-17.
Tu Q, Pi M, Quarles LD.
Calcyclin mediates serum response element (SRE) activation by an osteoblastic extracellular cation-sensing mechanism.
J Bone Miner Res. 2003 Oct;18(10):1825-33.
Rodova M, Islam MR, Peterson KR, Calvet JP.
Remarkable Sequence Conservation of the Last Intron in the PKD1 Gene.
Mol Biol Evol. 2003 Oct;20(10):1669-74.
Chapman AB, Guay-Woodford LM, Grantham JJ, Torres VE, Bae KT, Baumgarten DA, Kenney PJ, King
BF Jr, Glockner JF, Wetzel LH, Brummer ME, O'Neill WC, Robbin ML, Bennett WM,
Klahr S, Hirschman GH, Kimmel PL, Thompson PA, Miller JP; Consortium for
Radiologic Imaging Studies of Polycystic Kidney Disease cohort.
Renal structure in early autosomal-dominant polycystic kidney disease (ADPKD): The
Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease (CRISP)
cohort.
Kidney Int. 2003 Sep;64(3):1035-45.
Zhang J, Bai S, Zhang X, Nagase H, Sarras MP Jr.
The expression of gelatinase A (MMP-2) is required for normal development of zebrafish embryos.
Dev Genes Evol. 2003 Sep;213(9):456-63.
Grantham JJ
The kidney: from normal development to congenital disease: editors: peter d. Vize, adrian s. Woolf, and johnathan B.L. Bard publisher: academic press.
Am J Kidney Dis. 2003 Aug;42(2):427. No abstract available.
Weiss ML, Mitchell KE, Hix JE, Medicetty S, El-Zarkouny SZ, Grieger D, Troyer DL.
Transplantation of POrcine umbilical cord matrix cells into the rat brain.
Exp Neurol. 2003 Aug;182(2):288-9.
PMID:12895440 [PubMed- indexed for Medline]
Abrahamson DR, Robert B.
Derivation and differentiation of glomerular endothelial cells.
Nephrol Dial Transplant. 2003 Aug;18 Suppl 6:vi2-7.
Abrahamson DR.
Unveiling mesangial mysteries.
Kidney Int. 2003 Jul;64(1):363-4.
Gao Z, Ruden DM, Lu X
PKD2 cation channel is required for directional sperm movement and male fertility.
Curr Biol. 2003 Dec 16;13(24):2175-8.
PMID: 14680633 [PubMed - indexed for MEDLINE]
Helwig B, Schreurs KM, Hansen J, Hageman KS, Zbreski MG, McAllister RM, Mitchell KE, Musch TI.
Training-induced chenges in skeletal muscle Na+-K+ pump number and isoform expression in rats with chronic heart failure.
J Appl Physiol. 2003 Jun; 94(6):2225-4-36, Epub 2003 Jan 31
PMID: 12562669 [PUBMED- indesed for medline]
Mitchell KE, Weiss ML, Mitchell BM, Martin P, Davis D, Morales L, Helwig B, Beerenstrauch M, Abou-Easa K, Hlidreth T, Troyer D, Medicetty S.
Matrix cells from Wharton's jelly form neurons and glia.
Stem Cells. 2003;21(1);50-60. Erratum in: Stem Cells. 2003;21(2):247
PMID: 12529552 [Pudmed-indexed for MEDLINE]
Yamaguchi, T. S. Nagao, D.P. Wallace, F. Belibi, B.D. Cowley, Jr., J.C.
Pelling and J.J. Grantham.
cAMP activates B-Raf kinase and extracellular signal-regulated kinase (ERK) in epithelial cells from autosomal dominant polycystic kidneys.
Kidney Int. 2003 Jun; 63(6):1983-4
Zhang J, Bai S, Zhang X, Nagase H, Sarras MP Jr.
The expression of novel membrane-type matrix metalloproteinase isoforms is required for normal
development of zebrafish embryos.
Matrix Biol. 2003 May;22(3):279-93.
Calvet JP.
New insights into ciliary function: kidney cysts and photoreceptors.
Proc Natl Acad Sci U S A. 2003 May 13;100(10):5583-5.
Fujita M, Hawkinson D, King KV, Hall DH, Sakamoto H, Buechner M.
The role of the ELAV homologue EXC-7 in the development of the Caenorhabditis elegans excretory canals.
Dev Biol. 2003 Apr 15;256(2):290-301.
Troyer DL, Weiss ML, Mitchell KE, Martin PL,
Davis DL
Incorporation of bovine bone marrow stromal cells into porcine foetal tissues after xenotransplantation.
Anat Histol Embryol. 2003 Apr;32(2):98-101.
PMID: 12797531 [PubMed - indexed for MEDLINE]
Freeburg PB, Robert B, St John PL, Abrahamson DR.
Podocyte expression of hypoxia-inducible factor (HIF)-1 and HIF-2 during glomerular development.
J Am Soc Nephrol. 2003 Apr;14(4):927-38.
Abrahamson DR, Prettyman AC, Robert B, St John PL.
Laminin-1 reexpression in Alport mouse glomerular basement membranes.
Kidney Int. 2003 Mar;63(3):826-34.
Takahashi T, Takahashi K, St John PL, Fleming PA, Tomemori T, Watanabe T, Abrahamson DR, Drake CJ, Shirasawa T, Daniel TO.
A mutant receptor tyrosine phosphatase, CD148, causes defects in vascular development.
Mol Cell Biol. 2003 Mar;23(5):1817-31.
Calvet JP
Ciliary signaling goes down the tubes.
Nat Genet. 2003 Feb;33(2):113-4.
Nagao S, Yamaguchi T, Kusaka M, Maser RL, Takahashi H, Cowley BD, Grantham JJ.
Renal activation of extracellular signal-regulated kinase in rats with autosomal-dominant polycystic kidney disease.
Kidney Int. 2003 Feb;63(2):427-37.
Kaletta T, Van der Craen M, Van Geel A, Dewulf N, Bogaert T, Branden M, King KV, Buechner M, Barstead R, Hyink D, Li HP, Geng L, Burrow C, Wilson P. Related Articles, Links
Towards understanding the polycystins.
Nephron Exp Nephrol. 2003 Jan;93(1):e9-17.
Xiao, Zhou-Sheng, Simpson, L.G., Quarles, L.D.: IRES-Dependent Translational Control of Cbfa1/Runx2 Expression.
J. Cell. Biochem 2003 Feb 15;88:493-505.
Quarles, L.D., Sherrard, D.J., Adler, S., Rosansky, S.J., McCary, L.C., Liu, W., Turner, S.A., Bushinsky, D.A.: The calcimimetic AMG 073 as a potential treatment for secondary hyperparathyroidism of end-stage renal disease.
J Am Soc Neph 2003 Mar;14:575-583, 2003.
Tu, Q., Pi, M., Karsenty, G., Simpson, L.G., Liu, S., Quarles L.D.: Rescue of the Skeletal Phenotype in CasR-Deficient Mice by Transfer onto the Gcm2 Null Background.
J. Clin. Invest 2003 Apr; 111:1029-1037.
Weber, T.J., Liu, S., Indirdason, O.S., Quarles, L.D.: Serum FGF-23 Levels in Normal and Disordered Phosphorus Homeostasis.
J. Bone Miner. Res. 2003 Jul; 18:1227-1234, 2003.
Quarles, L.D.: FGF23, PHEX and MEPE Regulation of Phsophate Homeostasis and Skeletal Mineralization. AJP: Endocrinology and Metabolism 2003 Jul; 285(1):E1-E9.Quarles, L.D.:
Extracellular calcium-sensing receptors in tissues other than the parathyroid
gland and kidney, and other tissues.
Current Opinion in Nephrology and Hypertension 2003 Jul;12:349-355.
Chen, X., Garner, S.C., Quarles, L.D., Anderson, J.J.: Effects of genistein on expression of bone markers during MC3T3-E1 osteoblastic cell differentiation.
J. Nutr. Biochem 2003 Jun: 14(6):342-349, 2003.
Tu, Q., Pi, M., Quarles, L.D.: Calcyclin Mediates Serum Response Element (SRE)-Activation by
an Osteoblastic Extracellular Cation-Sensing Mechanism.
J Bone Miner. Res.Oct 2003; 18(10)1825-33,
Liu, S., Guo, R., Simpson, L.G., Xiao, Z.S., Burnham, C.E., Quarles, L.D.: Regulation of FGF23 expression but not degredation by Phex.
J. Biol. Chem. 2003 Sep 26; 278:37419-26.
Quarles, L.D.: Evidence for a bone-kidney axis regulating phosphate homeostasis.
J. Clin. Invest. Sep 112(5):642-646, 2003.
Wallace DP, Christensen M, Reif G, Belibi F, Thrasher B, Herrell D, Grantham JJ.
Electrolyte and fluid secretion by cultured human inner medullary collecting duct cells.
Am J Physiol Renal Physiol. 2002 Dec;283(6):F1337-50. Epub 2002 Jul 24.
Bao L, Spiller OB, St John PL, Haas M, Hack BK, Ren G, Cunningham PN, Doshi M,
Abrahamson DR, Morgan BP, Quigg RJ.
Decay-accelerating factor expression in the rat kidney is restricted to the apical surface of podocytes.
Kidney Int. 2002 Dec;62(6):2010-21.
Sullivan, L.P., D.P. Wallace, T. Grover, P.A. Welling, T. Yamaguchi, R. Maser, J.W. Eppler and J.J. Grantham.
Sulfonylurea sensitive K+ transport is involved in Cl secretion and cyst growth by cultured ADPKD cells.
J Am Soc Nephrol. 2002 Nov;13(11):2619-27.
Belibi, F.A., D.P. Wallace, T. Yamaguchi, M. Christensen, G. Reif and
J.J. Grantham.
The effect of caffeine on renal epithelial cells from patients with Autosomal Dominant Polycystic Kidney Disease.
J Am Soc Nephrol. 2002 Nov;13(11):2723-9.
Buechner M. Related Articles, Links
Tubes and the single C. elegans excretory cell.
Trends Cell Biol. 2002 Oct;12(10):479-84.
Carlin RW, Quesnell RR, Zheng L, Mitchell KE, Schultz BD.
Functional and molecular evidence for na(+)-HCO cotransporter in porcine vas deferens epithelia.
Am J Physiol Cell Physiol. 2002 Oct; 283(4):C1033-44.
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Calvet JP.
Cilia in PKD-Letting It All Hang Out.
J Am Soc Nephrol. 2002 Oct;13(10):2614-6. No abstract available.
Carlin RW, Quesnell RR, Zheng L, Mitchell KE, Schultz BD.
Functional and molecular evidence for Na(+)-HCO cotransporter in porcine vas deferens epithelia.
Am J Physiol Cell Physiol. 2002 Oct;283(4):C1033-44.
PMID: 12225967 [PubMed - indexed for MEDLINE]
Grantham JJ.
The Jeremiah Metzger Lecture. Polycystic kidney disease: old disease in a new context.
Trans Am Clin Climatol Assoc. 2002;113:211-24; discussion 224-6.
Guo R, Rowe PS, Liu S, Simpson LG, Xiao ZS, Darryl Quarles LD.
Inhibition of MEPE cleavage by Phex.
Biochem Biophys Res Commun. 2002 Sep 13;297(1):38-45.
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Sarras MP Jr, Yan L, Leontovich A, Zhang JS.
Structure, expression, and developmental function of early divergent forms of metalloproteinases in hydra.
Cell Res. 2002 Sep;12(3-4):163-76.
Rodova M, Islam MR, Maser RL, Calvet JP.
The polycystic kidney disease-1 promoter is a target of the beta-catenin/T-cell factor pathway.
J Biol Chem. 2002 Aug 16;277(33):29577-83.
Wolf D, Rodova M, Miska EA, Calvet JP, Kouzarides T.
Acetylation of beta-catenin by CREB-binding protein (CBP).
J Biol Chem. 2002 Jul 12;277(28):25562-7.
Finley MR, Li Y, Hua F, Lillich J, Mitchell KE, Ganta S, Gilmour RF Jr, Freeman LC.
Expression and coassociation of ERG1, KCNQ1, and KCNE1 potassium channel proteins in horse heart.
Am J Physiol Heart Circ Physiol. 2002 Jul;283(1):H126-38.
PMID: 12063283 [PubMed - indexed for MEDLINE]
Broughman JR, Shank LP,
Takeguchi W, Schultz BD, Iwamoto T, Mitchell KE, Tomich JM.
Distinct structural elements that direct solution aggregation and membrane assembly in the channel-forming peptide
M2GlyR.
Biochemistry. 2002 Jun 11;41(23):7350-8.
PMID: 12044167 [PubMed - indexed for MEDLINE]
Ledford AW, Brantley JG, Kemeny G, Foreman TL, Quaggin SE, Igarashi P, Oberhaus SM, Rodova M, Calvet JP, Vanden Heuvel GB.
Deregulated expression of the homeobox gene Cux-1 in transgenic mice results in downregulation of p27(kip1) expression during nephrogenesis, glomerular abnormalities, and multiorgan
hyperplasia.
Dev Biol. 2002 May 1;245(1):157-71.
Parnell SC, Magenheimer BS, Maser RL, Zien CA, Frischauf AM, Calvet JP.
Polycystin-1 activation of c-Jun N-terminal kinase and AP-1 is mediated by heterotrimeric G proteins.
J Biol Chem. 2002 May 31;277(22):19566-72.
Trefzer A, Blanco G, Remsing L, Kunzel E, Rix U, Lipata F, Brana AF, Mendez C, Rohr J, Bechthold A, Salas JA.
Rationally designed glycosylated premithramycins: hybrid aromatic polyketides using genes from three different biosynthetic pathways.
J Am Chem Soc. 2002 May 29;124(21):6056-62.
Maser RL, Vassmer D, Magenheimer BS, Calvet JP.
Oxidant stress and reduced antioxidant enzyme protection in polycystic kidney disease.
J Am Soc Nephrol. 2002 Apr;13(4):991-9.
Schwiebert EM, Wallace DP, Braunstein GM, King SR, Peti-Peterdi J, Hanaoka K, Guggino WB, Guay-Woodford LM, Bell PD, Sullivan LP, Grantham JJ, Taylor AL.
Autocrine extracellular purinergic signaling in epithelial cells derived from polycystic kidneys.
Am J Physiol Renal Physiol. 2002 Apr;282(4):F763-75.
Cabrera PV, Blanco G, Ernst G, Alvarez E, Cooper EL, Hajos S.
Coelomocyte locomotion in the sipunculan Themiste petricola induced by exogenous and endogenous
chemoattractants: role of a CD44-like antigen--HA interaction.
J Invertebr Pathol. 2002 Feb;79(2):111-9.
Shimizu H, Zhang X, Zhang J, Leontovich A, Fei K, Yan L, Sarras MP Jr.
Epithelial morphogenesis in hydra requires de novo expression of extracellular matrix components and matrix metalloproteinases.
Development. 2002 Mar;129(6):1521-32.
Syed BA, Beaumont NJ, Patel A, Naylor CE, Bayele HK, Joannou CL, Rowe PS, Evans RW, Srai SK.
Analysis of the human hephaestin gene and protein: comparative modelling of the N-terminus ecto-domain based upon ceruloplasmin.
Protein Eng. 2002 Mar;15(3):205-14.
PMID: 11932491 [PubMed - indexed for MEDLINE]
Grantham JJ, Wallace DP.
Return of the secretory kidney.
Am J Physiol Renal Physiol. 2002 Jan;282(1):F1-9. Review.
Liu, S., Guo, R., Tu, Q., Quarles, L.D.: Overexpression of Phex in osteoblasts fails to rescue the Hyp mouse phenotype.
J. Biol. Chem. 2002 Feb1;277(5):3686-3697
Spurney, R.F., Flannery, P.J., Garner, S.C., Athirakul, K., Liu, S., Guilak, F., Quarles, L.D.: Anabolic effects of a G protein-coupled receptor kinase inhibitor expressed in
osbeoblasts.
J. Clin. Invest 2002 May; 109(10):1361-71.
Mason DE, Mitchell KE, Li
Y, Finley MR, Freeman LC.
Molecular basis of
voltage-dependent potassium currents in porcine granulosa cells.
Mol Pharmacol. 2002 Jan;61(1):201-13.
PMID: 11752222 [PubMed - indexed for MEDLINE]
Quarles, L.D.: Advances in Hyperparathyroidism: Pathogenesis and Treatment, Guest Editor.
Advances in Renal Replacement Therapy. 2002 Jul;9:153-218.
Quarles, L.D.: Introduction: Emerging Therapies Derived from the Molecular Pathogenesis of
Secondary Hyperparathyroidism in ESRD Patients.
Advances in Renal
Replacement Therapy 2002 Jul; 9(3):153-158.
Indridason, O.S., and Quarles, L.D.: Hyperphosphatemia in End-Stage Renal Disease.
Advances in Renal Replacement Therapy 2002 Jul; 9:184-192.
Guo, R., Rowe, P.S.N., Liu, S., Quarles, L.D.: Inhibition of MEPE cleavage by Phex.
Biochem Biophys. Res. Commun. 2002 Sep 13;297(1):38-45, 2002.
Sutters M, Yamaguchi T, Maser RL, Magenheimer BS, St John PL, Abrahamson DR, Grantham JJ, Calvet JP.
Polycystin-1 transforms the cAMP growth-responsive phenotype of M-1 cells.
Kidney Int. 2001 Aug;60(2):484-94.
Grantham JJ.
Polycystic kidney disease: from the bedside to the gene and back.
Curr Opin Nephrol Hypertens. 2001 Jul;10(4):533-42.
Wallace DP, Rome LA, Sullivan LP, Grantham JJ.
cAMP-dependent fluid secretion in rat inner medullary collecting ducts.
Am J Physiol Renal Physiol. 2001 Jun;280(6):F1019-29.
Calvet JP, Grantham JJ.
The genetics and physiology of polycystic kidney disease.
Semin Nephrol. 2001 Mar;21(2):107-23. Review.
Broughman JR, Mitchell KE,
Sedlacek RL, Iwamoto T, Tomich JM, Schultz BD.
NH(2)-terminal modification of a channel-forming peptide increases capacity for epithelial
anion secretion.
Am J Physiol Cell Physiol. 2001 Mar;280(3):C451-8.
PMID: 11171563 [PubMed - indexed for MEDLINE]
Grantham JJ, Calvet JP.
Polycystic kidney disease: In danger of being X-rated?
Proc Natl Acad Sci U S A. 2001 Jan 30;98(3):790-2. Review. No abstract available.
Grantham JJ, Calvet JP.
Polycystic kidney disease: In danger of being X-rated?
Proc Natl Acad Sci U S A. 2001 Jan 30;98(3):790-2. Review. No abstract available.
Thomas JL, Mason JI, Blanco G, Veisaga ML.
The engineered, cytosolic form of human type I 3beta-hydroxysteroid dehydrogenase/isomerase: purification, characterization and crystallization.
J Mol Endocrinol. 2001 Aug;27(1):77-83.
Ma W, Tan J, Matsumoto H, Robert B, Abrahamson DR, Das SK, Dey SK.
Adult tissue angiogenesis: evidence for negative regulation by estrogen in the uterus.
Mol Endocrinol. 2001 Nov;15(11):1983-92.
Chambrey R, St John PL, Eladari D, Quentin F, Warnock DG, Abrahamson DR, Podevin RA, Paillard M.
Localization and functional characterization of Na+/H+ exchanger isoform NHE4 in rat thick ascending limbs.
Am J Physiol Renal Physiol. 2001 Oct;281(4):F707-17.
St John PL, Abrahamson DR.
Glomerular endothelial cells and podocytes jointly synthesize laminin-1 and –11 chains.
Kidney Int. 2001 Sep;60(3):1037-46.
Sequeira Lopez ML, Pentz ES, Robert B, Abrahamson DR, Gomez RA.
Embryonic origin and lineage of juxtaglomerular cells.
Am J Physiol Renal Physiol. 2001 Aug;281(2):F345-56.
Robert B, Abrahamson DR.
Control of glomerular capillary development by growth factor/receptor kinases.
Pediatr Nephrol. 2001 Mar;16(3):294-301. Review.
St John PL, Wang R, Yin Y, Miner JH, Robert B, Abrahamson DR.
Glomerular laminin isoform transitions: errors in metanephric culture are corrected by grafting.
Am J Physiol Renal Physiol. 2001 Apr;280(4):F695-705.
Sarras MP Jr, Deutzmann R.
Hydra and Niccolo Paganini (1782-1840)--two peas in a pod? The molecular basis of extracellular matrix structure in the invertebrate, Hydra.
Bioessays. 2001 Aug;23(8):716-24. Review.
Zhang J, Leontovich A, Sarras MP Jr.
Molecular and functional evidence for early divergence of an endothelin-like system during metazoan evolution: analysis of the Cnidarian, hydra.
Development. 2001 May;128(9):1607-15.
Sutters M, Yamaguchi T, Maser RL, Magenheimer BS, St John PL, Abrahamson DR, Grantham JJ, and Calvet JP:
Expression of a stably transfected C-terminal polycystin-1 construct transforms the cAMP
growth-responsive phenotype of M-1 cells.
Kidney Int. 60: 484-494, 2001.
Suzuki N, Buechner M, Nishiwaki K, Hall DH, Nakanishi H, Takai Y, Hisamoto N, Matsumoto K.
A putative GDP-GTP exchange factor is required for development of the excretory cell in
Caenorhabditis elegans.
EMBO Rep. 2001 Jun;2(6):530-5.
Xiao, Z.S., Liu, S.G., Hinson, T.K., Quarles, L.D.: Characterization of the upstream mouse Cbfa1/Runx2 promoter.
J Cellular Biochem 2001;82(4):647-659.
Quarles, L.D, Drezner, M.K.: Pathophysiology of X-linked hypophosphatemia, tumor-induced osteomalaci and autosomal dominant hypophosphatemia: a perPHEXing problem.
J Clin Endocrinol Metab 2001 Feb 86(2):494-496.
Garner, S.C., Pi, M., Tu, Q., Quarles. L.D.: Rickets in CasR deficient mice: An unexpected skeletal phenotype.
Endocrinology 2001 Sep;142 (9):3996-4005.
Liu, S., Guo, R., Quarles, L.D.: Cloning and characterization of the proximal murine Phex promoter. Endocrinology 2001 Sep; 142(9):3987-3995
Guo, R., Liu, S.G., Spurney, R.F., Quarles, L.D.: Analysis of recombinant Phex: An
endopeptidase in search of a substrate.
Am J Physiol Endocrinol Metab 2001 Oct,281(4):E837-847.
Xiao, Z.S., Quarles, L.D., Qing-Quan, C., Yan-Hui, Y., Xiang-Ping, Q., Chang-Hong, J., Han-Wu, D., Yuan-Jian, L., Hong-Hao,
Z: Effect of asymmetric dimethylarginine on osteoblastic differentiation.
Kidney Int 2001 Nov; 60(5):1699-1704.
Quarles, L.D.: Bone biopsy and the diagnosis of renal osteodystrophy.
In: UPTODATE in Nephrology and Hypertension; Vol. 9.3, Rose, B.D., editor, BDR, Inc., 2001 9.
Quarles, L.D., Cronin,
R.: Calcitriol supplementation in advanced chronic renal failure.
In: UPTODATE in Nephrology and Hypertension; Vol. 9.3, Rose, B.D., editor, BDR, Inc., 2001.
Rocha, P.N., Agus, Z.,
Berkoben, M., Quarles, L.D.: Hungry bone syndrome following parathyroidectomy.
In: UPTODATE in Nephrology and Hypertension; Vol. 9.3, Rose, B.D., editor, BDR, Inc., 2001
Rocha, P.N., Berkoben, M., Cronin, R., Quarles, L.D.: Indications for parathyroidectomy in end-stage renal disease.
In: UPTODATE in Nephrology
and Hypertension; Vol. 9.3, Rose, B.D., editor, BDR, Inc., 2001
Butterly, D., Quarles, L.D.:
Parathyroid and mineral metabolism after renal transplantation.
In: UPTODATE in Nephrology
and Hypertension; Vol. 9.3, Rose, B.D., editor, BDR, Inc., 2001
Quarles, L.D.: Bone
biopsy and the diagnosis of renal osteodystrophy.
In: UPTODATE in Nephrology
and Hypertension; Vol. 9.3, Rose, B.D., editor, BDR, Inc., 2001
Griffith, T.K., Hartle, J.E., Quarles, L.D.: Calciphylaxis;
In: UPTODATE in Nephrology
and Hypertension; Vol. 9.3, Rose, B.D., editor, BDR, Inc., 2001.
Sise C, Kusaka M, Wetzel LH, Winklhofer F, Cowley BD, Cook LT, Gordon M, Grantham JJ.
Volumetric determination of
progression in autosomal dominant polycystic kidney disease by computed
tomography.
Kidney Int. 2000 Dec;58(6):2492-501.
Rowe PS, de Zoysa PA, Dong R, Wang HR, White KE, Econs MJ, Oudet CL.
MEPE, a new gene expressed in bone marrow and tumors causing osteomalacia.
Genomics. 2000 Jul 1;67(1):54-68.
PMID: 10945470 [PubMed - indexed for MEDLINE]
Yamaguchi T, Pelling JC, Ramaswamy NT, Eppler JW, Wallace DP, Nagao S, Rome LA, Sullivan LP, Grantham JJ.
cAMP stimulates the in vitro proliferation of renal cyst epithelial cells by activating the extracellular signal-regulated kinase pathway.
Kidney Int. 2000 Apr;57(4):1460-71.
Wallace DP, Tomich JM, Eppler JW, Iwamoto T, Grantham JJ, Sullivan LP.
A synthetic channel-forming peptide induces Cl(-) secretion: modulation by Ca(2+)-dependent K(+) channels.
Biochim Biophys Acta. 2000 Mar 15;1464(1):69-82.
Nagao S, Yamaguchi T, Kasahara M, Kusaka M, Matsuda J, Ogiso N, Takahashi H, Grantham JJ.
Effect of probucol in a murine model of slowly progressive polycystic kidney disease.
Am J Kidney Dis. 2000 Feb;35(2):221-6.
Grantham JJ.
Time to treat polycystic kidney
diseases like the neoplastic disorders that they are.
Kidney Int. 2000 Jan;57(1):339-40. No abstract available.
Fei K, Yan L, Zhang J, Sarras MP
Jr.
Molecular and biological characterization of a zonula occludens-1 homologue in Hydra vulgaris, named HZO-1.
Dev Genes Evol. 2000 Dec;210(12):611-6.
Ricker JL, Gattone VH 2nd, Calvet JP, Rankin CA.
Development of autosomal recessive polycystic kidney disease in BALB/c-cpk/cpk mice.
J Am Soc Nephrol. 2000 Oct;11(10):1837-47.
Yan L, Fei K, Bridge D, Sarras MP Jr.
A cnidarian homologue of translationally controlled tumor protein (P23/TCTP).
Dev Genes Evol. 2000 Oct;210(10):507-11.
Deutzmann R, Fowler S, Zhang X, Boone K, Dexter S, Boot-Handford RP, Rachel R, Sarras MP Jr.
Molecular, biochemical and functional analysis of a novel and developmentally important fibrillar collagen (Hcol-I) in hydra.
Development. 2000 Nov;127(21):4669-80.
Fowler SJ, Jose S, Zhang X, Deutzmann R, Sarras MP Jr, Boot-Handford RP.
Characterization of hydra type IV collagen. Type IV collagen is essential for head regeneration and its expression is up-regulated upon exposure to glucose.
J Biol Chem. 2000 Dec 15;275(50):39589-99.
Rowe PS, de Zoysa PA, Dong R, Wang HR, White KE, Econs MJ, Oudet CL.
MEPE, a new gene expressed in bone marrow and tumors causing osteomalacia.
Genomics. 2000 Jul 1;67(1):54-68.
PMID: 10945470 [PubMed - indexed for MEDLINE]
Yan L, Leontovich A, Fei K, Sarras MP Jr.
Hydra metalloproteinase 1: a secreted astacin metalloproteinase whose apical axis expression is
differentially regulated during head regeneration.
Dev Biol. 2000 Mar 1;219(1):115-28.
Petitclerc E, Boutaud A, Prestayko A, Xu J, Sado Y, Ninomiya Y, Sarras MP Jr, Hudson BG, Brooks PC.
New functions for non-collagenous domains of human collagen type IV. Novel integrin ligands inhibiting angiogenesis and tumor growth in vivo.
J Biol Chem. 2000 Mar 17;275(11):8051-61.
Yan L, Fei K, Zhang J, Dexter S, Sarras MP Jr.
Identification and characterization of hydra metalloproteinase 2 (HMP2): a meprin-like astacin
metalloproteinase that functions in foot morphogenesis.
Development. 2000 Jan;127(1):129-41.
Leontovich AA, Zhang J,
Shimokawa K, Nagase H, Sarras MP Jr.
A novel hydra matrix metalloproteinase (HMMP) functions in extracellular matrix degradation,
morphogenesis and the maintenance of differentiated cells in the foot process.
Development. 2000 Feb;127(4):907-20.
Wallace, D.P., J.M. Tomich, J.W. Eppler, T. Iwamoto, J.J. Grantham, and L.P. Sullivan.
A synthetic channel-forming peptide induces Cl-secretion: Modulation by Ca2+-dependent K+ channels.
Biochim et Biophys Acta 1464: 69-82, 2000.
Robert B, Zhao X, Abrahamson DR.
Coexpression of neuropilin-1, Flk1, and VEGF(164) in developing and mature mouse kidney glomeruli.
Am J Physiol Renal Physiol. 2000 Aug;279(2):F275-82.
Wang R, St John PL, Kretzler M, Wiggins RC, Abrahamson DR.
Molecular cloning, expression, and distribution of glomerular epithelial protein 1 in developing mouse kidney.
Kidney Int. 2000 May;57(5):1847-59.
Peti-Peterdi J, Chambrey R, Bebok Z, Biemesderfer D, St John PL, Abrahamson DR, Warnock DG, Bell PD.
Macula densa Na(+)/H(+) exchange
activities mediated by apical NHE2 and basolateral NHE4 isoforms.
Am J Physiol Renal Physiol. 2000 Mar;278(3):F452-63.
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The University of Kansas Medical Center