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Nephrology and Hypertension

The Division of Nephrology & Hypertension at KUMC is known for its excellent clinical program and world-class translational and basic research activities. Here, physician-scientists, basic scientists, and clinicians have distinguished themselves among their peers for work in polycystic kidney disease, bone and mineral metabolism, kidney development, and transplantation. Our clinical program is equally strong, with master clinicians and a number of young clinical nephrologists who are deeply committed to patient care. That commitment is demonstrated in the high level of patient outcomes that the transplant program has delivered, in the inpatient consult service that provides state-of-the-art hemodialysis therapies, and in the outpatient hemodialysis and home dialysis programs. A total of ten physicians participate in the clinical, research and educational initiatives in this division.

We have coupled these strong clinical and research programs with a fellowship program designed to train future nephrologists, as well as those who will become physician-scientists.  Six trainees are currently enrolled in our ACGME-accredited fellowship program. Four are pursuing a two-year clinical fellowship, while two are pursuing a three-year clinical/basic science and research fellowship. In recognition of the merits of our program, we have been awarded a training grant from the National Institutes of Health.

Seven members of the division are basic/translational researchers who are unraveling the complexities of abnormal mineral metabolism in chronic kidney disease and discovering novel hormonal regulatory pathways concerning phosphate homeostasis. In particular, research into the pathogenesis of polycystic kidney disease is on the verge of discoveries leading to new therapies to treat this prominent cause of chronic kidney failure. In addition, discoveries related to FGF23 function and calcium-sensing receptors herald new approaches to treating hyperphosphatemia and metabolic bone disease in end-stage renal diseases. Another of our research teams is investigating the development of the glomerulus during kidney organo-genesis, using a variety of molecular genetic, cell and organ culture, immunocytochemical, and transembryonic microsurgical grafting approaches. In another lab, investigators are studying the effects of injurious agents and disease states as well as the effects of protective agents on glomerular permeability.

The Division of Nephrology is an integral part of the Kidney Institute, which serves as a model for developing a comprehensive, multidisciplinary approach to the prevention, diagnosis and treatment of kidney disease. The Kidney Institute is comprised of faculty, fellows, and research associates across departments and disciplines. The extensive interdepartmental participation reflects a collegial atmosphere that allows established investigators and trainees alike to take full advantage of the scientific resources that KU has to offer.

Faculty

Arnold Chonko, M.D., F.A.C.P.
Dennis Diederich, M.D., F.A.C.P.
Ellen McCarthy, M.D.
Min Pi, Ph.D.
L. Darryl Quarles, M.D.
Brian Ringhofer, M.D.
Jason Stubbs, M.D.
Darren Wallace, Ph.D.
Connie Wang, M.D.
James Wetmore, M.D.
Franz Winklhofer, M.D.
Zhousheng Xiao, MD, PhD
Sri Yarlagadda, M.D.

Divisional Contacts


Academic Contacts

L. Darryl Quarles, M.D.
Nephrology Fellowship Program Director
913-588-9252

Krissy Hembree
Fellowship Coordinator
913-588-6075
khembree@kumc.edu

Clinical Contact

New Patients: 
Phyllis Swafford and Debbie Alcanter
Division of Nephrology
MS 3002, 3901 Rainbow Blvd.
Kansas City, KS 66160
Phone:  913-588-6074
Fax:  913-588-3867

Return Patients:
Lori Kirkendoll
1124, Suite E KU Hospital
Mail Stop 0
3901 Rainbow Boulevard
Kansas City, KS 66160
Phone:  913-588-4083
Fax:  913-588-0440