The Importance of a Pedigree
Using a Punnett Square
What is the Hardy-Weinberg Equation?
Case 1 - Marfan Syndrome
Case 2 - Cystic Fibrosis
Case 3 - Hemophilia
Case 4 - Hypophosphatemic
Case 5 - Leber
Hereditary Optic Atrophy
Case 6 - Albinism
Case 7 - Duchenne
A Punnett Square can help determine the probability that offspring will
have a particular phenotype or genotype.
Example: The possible offspring outcomes for parents who are both carriers of a cystic fibrosis mutation.
C- normal allele
c- allele with CF mutation
In this example, each child would have:
25% chance of being unaffected with Cystic Fibrosis (CC)
50% chance of being a carrier of Cystic Fibrosis (Cc)
25% chance of being affected with Cystic Fibrosis (cc)