JULY 2001

 

 

We would like to devote this Special Pharmacy Key to welcome you to the University of Kansas Hospital.  We would like to review the services provided by the Department of Pharmacy, institutional policies concerning drug use in the hospital and suggested guidelines for prescription writing.  The goal of this publication is to foster an understanding of pharmacy services and medication use policies so that safe, efficient and rational drug use or therapy may continue in this institution.

 

CLINICAL PHARMACY TEAMS

 

Patient Care units at University of Kansas Hospital are divided among pharmacy teams.  Coverage during evening and weekend shifts varies slightly.  Clinical Pharmacists carry pagers for accessibility and nursing unit staff or central pharmacy can provide the pager number for designated pharmacists.

 

Clinical Pharmacists:

Pager

DAY (0800-1500)

 

Team 1 (PED,PICU, 56, 54LDR)

7972

Team 2 (Cardiology: 46, 44A)

7936

Team 3 (Med/CTS: 41, 45, 52, 53 : 2 RPhs)

7908/7958

Team 4 (Trauma/Surg ICU: SIC, 51, 15's)

7964

Team 5 (Heme/Onc: 42, MTU)

7956

Team 6 (MICU-not 44A, 43, Pt Ed 30F, 27, 37)

7970

EVENING (1500-2300)

 

Team 1E (PED,NICU, PICU, 56, 54LDR)

7972

Team 2E (Cardio/MIC: 46, MIC, 44A, 51)

7936

Team 3E (41, 53, 52)

7958

Team 4E (Trauma/CTS: SIC, 45, 15's)

7964

Team 5E (Heme/Onc: 42, MTU, 43)

7956

Central (27,30F)

Ext.82321

2300-0800

Ext.82321

 

 

 

 

 

 

Prescription Order Writing Tips

 

From the National Coordinating Council for Medication Error Reporting and Prevention

 

·      Always write legibly

·      When possible include intended purpose

·      All orders should be written in the metric system except for orders that use standard units such as insulin and vitamins

·      Spell out units rather than using "U"

·      Include age and weight when appropriate

·      All medication orders should include drug name, exact metric dose or concentration and dosage form

·      A leading zero should always precede a decimal expression of less than one.

(0.1 mg….YES!!)

·      Trailing zeros should never be used (1.0 mg ….NO!)

Avoid using abbreviation including those for the drug name (i.e., MOM, HCTZ)

 

 

 

 

PHARMACY SERVICES AT THE

UNIVERSITY OF KANSAS HOSPITAL

 

The Department of Pharmacy provides comprehensive, 24-hour service to patients, physicians and staff as an integral part of the teaching, research and patient care programs at The University of Kansas Hospital.

 

CLINICAL PHARMACY SERVICES

 

Pharmacy Services for inpatients are provided by decentralized Clinical Pharmacists. The clinical pharmacist responsible for the medical service and/or nursing unit caring for your patients is an excellent resource.  This pharmacist is your best liaison with the central Department of Pharmacy when drug-related questions or problems and any special requests arise.

 

The Clinical Pharmacist is responsible for review of the patient medication regimen.  Pharmacists screen for potential problems with medication orders: dosing, drug allergies, drug interactions, intravenous incompatibility and more.  Physicians are informed of potential problems and possible drug therapy modification.  Pharmacists are actively involved in monitoring drug therapy and provide pharmacokinetic dosing for selected antimicrobials.  Patient education during the hospital stay and/or upon discharge maybe provided by Clinical Pharmacists.  A Self-Medication Educational Program for patients and medication calendars are available for patients with multiple medications and compliance problems.

 

Pharmacy notes located in the patient chart may and/or the electronic medical record, contain information regarding patient education, compliance assessment, pharmacokinetic dosing or other information related to patient drug therapy decisions.

 

 

 

 

 

THE FORMULARY SYSTEM

 

The Formulary System is the accepted method approved by the Medical Staff whereby physicians select medications to be available for University Of Kansas Hospital patients. The Pharmacy and Therapeutics Committee evaluates, appraises and selects from the numerous medical agents commercially available and makes recommendations to the Executive Committee of the Medical Staff indicating medications which are the preferred medications for patient care at University Of Kansas Hospital.  These recommendations require approval by the Executive Committee of the Medical Staff prior to formulary inclusion.   The evaluation of drugs for admission into the Formulary System is comprehensive and considers efficacy, safety, and economic issues, all aimed at promoting rational, cost-effective drug therapy.  It also includes comparisons of therapeutic alternatives to minimize therapeutic duplication in the formulary.  The University Of Kansas Hospital Formulary is the published list of approved medications considered most useful in providing care for the vast majority of patients, both inpatient and outpatient, in the University Of Kansas Hospital Health System.  University of Kansas Hospital prescribers are expected to prescribe these approved formulary medications.  If medically necessary, non-formulary medications can be obtained upon request for specific patients during their hospital stay.

 

 

 

REQUEST FOR NON-FORMULARY DRUGS

 

When a non-formulary drug is requested, the pharmacist will inform the prescribing physician of formulary alternatives, which are therapeutically equivalent, and of their proper dosage.  If an acceptable formulary medication is not identified, the Pharmacy will obtain a small supply of the drug for that particular patient. A nonformulary service fee fee incurred will be billed to the patient.  A time delay of 24-48 hours should be anticipated since the drugs must be ordered from outside source.

 

The non-formulary drug may be sent home with the patient as a dismissal medication, if written for, but will be limited to only the remaining supply.  It is recommended that another prescription be sent with the patient for any additional quantity necessary.

 

If a physician intends to prescribe a non-formulary drug on a regular basis, it is recommended that a request for evaluation for Formulary admission be submitted.

 

FORMULARY ADDITIONS AND DELETIONS

 

Requests for additions to or deletions from the University of Kansas Hospital Formulary should be submitted to the Director of Pharmacy on the Application for Formulary Admission Form to facilitate consideration by the Pharmacy and Therapeutics Committee.  Such requests must be approved by the Chairman of the Department desiring the drug.  Applications must be complete and must include sufficient supportive data to enable the committee to make a sound decision.  Application forms are available from the Department of Pharmacy or on the University of Kansas Hospital Pulse at the following url: http://www2.kumc.edu/pharmacy/formrequest.html.  All drugs are admitted on a nonproprietary name (generic) basis.  No drug of unknown or secret composition will be admitted.

 

All drug additions and deletions to the formulary must be subsequently approved by the Executive Committee of the Medical Staff.  Drugs added or deleted from the formulary will be announced in the Pharmacy newsletter, the Pharmacy Key.  The effective date of the addition or deletion will be noted in the publication of the Pharmacy Key. The Pharmacy Key can be accessed via the Internet at the following url:http://www2.kumc.edu/druginfo/pharmkey.html.   

 

DRUG DISTRIBUTION

 

Unit floor stock is available from Pyxis units on all patient care units and many diagnostic units.  This automation allows authorized health care professionals to access medications that are on a patient profile and medications that are considered “PRN” for an individual unit.  Biometric "passwrods" (e.g. fingerprint) scanners are used to ensure positive identification for Pyxis machine access.

 

The medications available in each Pyxis unit are chosen by each nursing unit and its pharmacist.  The availability of each medication is based upon safety, usage and stability.  Prescribed medications that are not available in Pyxis units are delivered to patient care areas by the Department of Pharmacy in individual packages which identify each dose (unit dose packaging). 

 

SAMPLES

 

Professional drug samples are not to be administered to inpatients.  Samples are not to be stored on the nursing units or hospital patient care areas.

 

PATIENT’S OWN MEDICATION POLICY

   

The hospital encourages the use of medications supplied and administered by the hospital at all times.  Patients may be permitted to use their own medications only under specific limited circumstances.  This limitation is based on patient safety with product integrity and potential self-administration of incorrect dosages being issues of concern.  In addition, the risk of medication error is increased by the use of medications outside of the normal medication use system. 

 

Handling of patient’s own medications is a time consuming process.  Order clarification, medication identification, documentation, special storage procedures and administration of these medications outside of the normal system consume valuable hospital resources.  It is prudent to consider the following procedures when making the decision to use patient’s own medications.

 

When May an Order for Patient’s Own Medication Be Appropriate?

 

      The medication is not on the hospital formulary and a reasonable therapeutic substitution is not available.  Consult with the nursing unit pharmacist if needed.

      Rarely, a formulary medication may be used from the patient’s personal supply when the physician, pharmacist, and patient deem the use medically necessary to meet a specific health care need. 

      The medication is an investigational or study medication provided under protocol as part of the patient’s participation in an investigational study. Medications that are not provided by the study shall be obtained through the pharmacy.

 

Patient’s own medication must be contained in the original prescription container that is properly labeled as required by state and federal laws, identifying the name, strength, dose, route, and directions for use of the medication.  Study medications may contain information as allowed by the study protocol and must be labeled with the patient name. If it is deemed necessary for a patient to use their medication from home, based on the guidelines above, specific written orders are required. An order stating only that “the patient may use his or her own medications” will not be accepted.  Medications to be supplied by the pharmacy must be ordered separately from the patient’s own medication order. 

 

How to Write an Order for a Patient’s Own Medication

 

      A statement that the “patient may use their own supply” while in the hospital.

      List only the medications that the patient is going to supply.

      Name, dose, route, and directions for each medication

 

Accurate identification of patient’s own medication is vital to the health care outcomes and safety of the patient.  JCAHO standards require that the clinical pharmacist identify each medication the patient is to use from their own supply to ensure that they are receiving the appropriate medication. Identification needs to be completed prior to administration of medication to the patient.

 

 

Storage of Patient’s Own Medication

 

Patients should be encouraged to send their own medications that are not being utilized at KUMC home with a family member or friend.  Patient’s own medication that remains in the hospital shall be securely stored on the nursing unit. These medications will be stored either in the “Patients Own Medication” section of the Pyxis® unit or in another locked cabinet on the unit.

 

Administration of Patient’s Own Medication

 

Administration of patient’s own medication is similar to the administration of medication dispensed by the pharmacy.  A nurse shall obtain the appropriate medication at the appropriate time from the patient’s own supply in the Pyxis® or other locked area.  This administration shall be documented on the medication administration record (MAR) indicating the medication, dose, and time given.  It is discouraged that a patient’s own medication be kept at their bedside, but if it is necessary to do so, the patient’s own medication order must also include the statement ”patient may keep their own medications at bedside”.  Controlled substances, however, may not be kept at the patient’s bedside.  The nurse shall observe the patient taking their bedside medication and document on the MAR the medication, dose, and time taken.

 

INTRAVENOUS ADMIXTURE SERVICE

 

The Department of Pharmacy prepares all intravenous drug admixtures.  The policy ensures that all solutions are prepared under aseptic conditions and are screened for drug interactions and incompatibilities.  Standard infusion concentrations have been established for several intravenous drugs.  Medication orders for these drugs should be written in the concentrations that have been established. Except for reasons of stability, compatibility, and/or volume problems, the standard diluent used in intravenous “piggyback” orders is D5W 50mL.

 

A list of Standard and maximum allowable concentrations for adult intravenous medications can be found in the May 2001 Pharmacy Key which is located at the following url:  http://www2.kumc.edu/druginfo/pharmkey.html

 

 

 

TOTAL PARENTERAL NUTRITION

 

·      The standard hang time for all adult and pediatric TPN solutions is 20:00.

·      Neonatal TPNs are hung between 1500 - 1700

·      All TPN orders for adults and pediatric patients are due in Pharmacy by 14:00.  This includes new and changed orders. Changes in neonatal orders are due in the Pharmacy by 1300

·      For adult and pediatric patients, the pharmacy will compound the 24 hr supply of TPN for a patient based on the orders in the Pharmacy at 14:00 and these solutions will be delivered to the nursing unit by 19:30. Neonatal TPNs will be delivered by 1500.

·      When a new TPN order is received after 14:00 for an adult or pediatric TPN, the pharmacist will contact the prescribing physician to determine when the order will need to be processed and if it can be scheduled for delivery the next day at 20:00.

 

MEDICATION ORDER TURN AROUND TIME

 

To prioritize the processing of new medication orders and to establish an appropriate turnaround time for these orders. The following turnaround times have been established:

 

1.    STAT:  Stat orders are defined as emergency medications (medications that are needed only in life threatening situations) and so written by the prescribing physician.  The physician should call a STAT order to the attention of the nurse so it can be taken off the chart immediately.  Pharmacy can fill these orders in five (5) minutes if the order is called down to the central pharmacy.

2.    ASAP/NOW:  ASAP or NOW orders will be written as such by the prescribing physician.  These orders will be delivered to the nursing unit within 30 minutes from the time pharmacy receives the written order. Exception:  Chemotherapy will be delivered within 2 hours from the time pharmacy receives the written order.

3.    ROUTINE ORDERS: Routine orders are all orders not written as  STAT, ASAP or NOW.  Routine orders will be delivered within two (2) hours from the time pharmacy receives them.

 

 


SCHEDULED TIMES FOR MEDICATIONS

 

Standard schedules have been established for medication administration. Exceptions to this schedule include selected drugs where levels may be affected by administration time and upon special request by the prescribing physician.

 

PROCEDURE:

1.    It is the responsibility of the physician, nurse and/or clinical pharmacist to indicate the appropriate time schedule for the drug on the order or pharmacy requisition.

2.    If a time schedule is not indicated on the order, the following schedules will be used:

QDAY

0900

Q2H

02-04-06-08, etc.

QAM

0900

Q4H

09-13-17-21-01-05

Daily

0900

Q6H

06-12-18-24

QHS

2100

Q6H alt

09-15-21-03

QPM

2100

Q8H

06-14-22

BID

09-21

Q8H alt

09-17-01

BID alt

08-17

Q12H

09-21

TID

09-15-21

Q12H alt

01-13

TID ac

07-11-17

Q24H

09

TID pc

09-13-19

 

 

TID W/MEALS

08-12-17

 

 

ACHS

07-11-17-21

 

 

QID

09-13-17-21

 

 

5XD

09-12-15-18-21

 

 

 

*These schedules are to be determined by when the order is received in the pharmacy and what the turn around time for the order needs to be.

 

Special Schedules:

Unit specific schedules will be limited to the following:

 

37

TID

09-13-21

27

BID

08-20

 

TID

08-12-20

 

QID

08-12-16-20

 

HS

20

46

Q6H

05-11-17-23

 

Q8H

06-14-22

 

QID verses Q6H schedules are not interchangeable and will be interpreted strictly as indicated above unless the clinical pharmacist suggests a different time schedule is more appropriate and indicates that schedule on the pharmacy requisition.

 

 

Outpatient Services and Prescriptions

 

Outpatients cared for by the University of Kansas Hospital are covered by a variety of health insurance programs. Reimbursement practices/requirements, preferred medications and formularies of various programs differ greatly. To provide comprehensive pharmacy services to all outpatients, the Outpatient Pharmacy maintains a drug inventory, which not only includes the University of Kansas Hospital formulary medications but additional medications as well. While  the University of Kansas Hospital prescribers are encouraged to utilize our preferred medications, other medications are also available.

 

Prescriptions filled in the Outpatient Pharmacy must be written only on a University of Kansas Hospital prescription blank by the University of Kansas Hospital Medical Staff and the patient must be a patient of the University of Kansas Hospital. However, verifiable prescriptions from local physicians may be filled for employees.    Prescriptions written by medical students must be countersigned by a staff physician.  The Physician’s name must be legibly printed or stamped on the prescription in addition to the signature. The KU Outpatient Pharmacy is open 8:00am - 7:00pm Monday thru Friday and 9:00am - 3:00pm Saturday and Sunday and most holidays.

 

CONTROLLED SUBSTANCES: Schedule II prescriptions must be written on green blanks. All other prescriptions, including Schedule III, IV and V are to be written on University of Kansas Hospital buff-colored prescription blanks labeled "Not Valid for Schedule II Prescriptions". All prescriptions written for controlled Substances (Schedule II - Schedule V) MUST be written by a physician possessing a Drug Enforcement Administration (DEA) registration number.   All new staff must sign a signature card to be maintained in the Outpatient Pharmacy.  All prescriptions written for Controlled Substances must bear the name and address of the patient, the current date and the DEA number. Refills on Schedule II prescriptions are not permitted.

 

DISMISSAL PRESCRIPTIONS:  Prescriptions for dismissal medications should be written on the Take Home Medication Form, which can be perforated into four individual prescriptions. Keep in mind that the patient may already have sufficient quantities of maintenance medications at home and additional quantities will not be reimbursed by prescription plans.  The physician must complete all appropriate information on each of the four prescription blanks used and VOID any unused sections of the form.  A signature is required for each prescription and the DEA number must be included on any prescriptions for controlled substances.  As a convenience,  patients may have take home medications filled in the University of Kansas Hospital Outpatient Pharmacy by faxing the order form to ext. 82385. Patients will be expected to provide any prescription insurance information, co-payments required by their prescription plan or the full prescription amount at the time of service.  The second copy of the form will stay in the patient's chart and the original copy is exchanged for the medications at the University of Kansas Hospital Outpatient Pharmacy or taken by the patient to the pharmacy of their choice.  Writing prescriptions 24 hours prior to discharge prevents a long wait for patients ready to go home and allows time to resolve financial issues that may arise.

 

DIRECTIONS:  Prescriptions written for outpatients must include adequate directions for the patient.  The use of "Take as Directed" does not provide these patients with adequate directions on the prescription label to insure proper dosage.  All prescriptions filled by the Pharmacy will be labeled with the name and strength of the medication.

 

QUANTITIES: Outpatient prescription quantities are limited to no more than a one-year supply [six months on controlled drugs-CIII to CV and 30 days for CII drugs] if so authorized.  The medical staff authorizes the University of Kansas Hospital Pharmacy to dispense lesser quantities of medication than prescribed per patient request and / or third party payor limitations.  The medical staff also authorizes the University of Kansas Hospital Pharmacy to provide equivalent dose and quantity adjustments of an identified drug on the prescription if required.  Such changes shall be documented on the prescription by the dispensing pharmacist.

 

REFILLS:  Prescriptions may not be refilled unless the physician specifies the number of refills to be permitted in the lower left hand corner of the prescription blank, where the following is printed:  "Refill _____ times".  Prescriptions written at the University of Kansas Hospital may be refilled in the Outpatient Pharmacy for not longer than one year for non-controlled drugs and 6 months or 5 refills for schedule III, IV and V Controlled Substances per Kansas State Law.  Schedule II medications are not refillable and require a new written prescription for each dispensing.

 

REFILL AUTHORIZATION CLINIC: The medical staff authorizes the outpatient pharmacy to provide an additional 30-day supply of medications to patients who have no remaining refills.  The medications that have been approved for this service include the following: antihypertensives, insulin, hormones, diabetic medications, asthma medications to include inhalers, nonsteroidal anti-inflammatory medications, seizure medications, DDI, Retrovir, immunosuppressant medications, and OTC drugs.  The outpatient pharmacist mails a Refill Clinic Notification Form to the prescribing physician.  The physician may phone in a new prescription to the pharmacy, mail a new prescription to the patient, or document the need for medication evaluation in the patient’s chart for the next clinic visit. Under no circumstances will the pharmacy issue a second supply without a new prescription from the physician.

 

TELEPHONE PRESCRIPTION ORDERS:  The Department of Pharmacy will accept phone-in prescriptions for KU outpatients and employees where federal and state law allows.  The pharmacy cannot accept telephoned orders for Schedule II drugs due to the Drug Enforcement Administration regulations restricting such activity.  Phone-in prescriptions will not be accepted for routine dismissal prescriptions.

 

INVESTIGATIONAL DRUGS

 

The Investigational Drug Service at the University of Kansas Hospital offers a range of research activities to ensure the safe delivery of quality health care for patients participating in an investigational drug trial.  In support of  the Department of Pharmacy’s mission, this service assures appropriate procurement, storage, handling, drug accountability, and information access about the investigational agents utilized.  The Investigational Drug Service also supports and complies with hospital policy, JCAHO, state and federal standards.  The goal of this service is to assist and support investigators in meeting their obligations in conducting clinical drug research at the University of Kansas while promoting safe and rational therapy for the patient.

The design of the study and the objectives of the investigator determine services needed by Investigational Drug Services.  A fee for Investigational Drug Services will be based upon the level of involvement required or requested as part of the clinical trial.