Southeast Kansas Health Study
III. Narrative Statement
During
public hearings in 1995 and 1996 on the permitting of Ash Grove Cement
Company in Chanute, Kansas, residents expressed concern over the
possible health effects of four hazardous waste combustors operating in
the area. To respond to these concerns, the U.S. Environmental
Protection Agency commissioned the University of Kansas Medical Center
to conduct a health study to determine if environmental releases from
hazardous waste burners and other industries in the cities of Chanute,
Coffeyville, Fredonia, and Independence, Kansas, could be associated
with health problems in these communities.
This document outlines the final protocol of a study to evaluate human health and air quality in these four communities and a control community of Sedan, Kansas, to ascertain whether or not an association exists between health problems in the communities and environmental factors. The study has three components:(1) a respiratory health survey and medical evaluation; (2) an epidemiological investigation of cancer incidence and mortality rates; and (3) an environmental assessment that includes the review of existing air monitoring data from the study communities, and the collection and analysis of ambient air samples from study and control communities over a one-year period during the study. (The detailed environmental monitoring assessment plan is attached to this document as Appendix A.)
The study's respiratory health component includes administering health questionnaires to randomly chosen households in the study and control communities. Based on the returned questionnaires as well as patient information collected from hospitals in the study and control communities on emergency room visits for acute respiratory illness, individuals who appear to be at elevated risk for adverse respiratory outcomes will be identified, and a sample group of approximately 250 individuals will be randomly selected to participate in a one-year respiratory health medical evaluation. Tally sheets also will be kept on inhaler use in schools in the study and control communities for a one-year period during the study.In the final phase of the study, all respiratory health data collected for the study and control communities will be compared, and environmental and medical data will be examined for associations between environmental factors and adverse respiratory outcomes.
The epidemiological investigation of cancer incidence and mortality rates builds upon an earlier preliminary epidemiological study of pediatric cancers in the area performed by the Kansas Department of Health and Environment This follow-on study will evaluate cancer incidence and mortality rates in the study and control areas. Data for this portion of the study will be abstracted from the vital records section of the Kansas Department of Health and Environment, the Kansas Cancer Registry, and the National Cancer Institute's Surveillance, Epidemiology and End Result (SEER) program. The cancer incidence and mortality rates of the study and control counties will be compared and then examined in relation to environmental data on toxic agents of exposure in air to residents of the study areas. Data on cancer incidence and prevalence will also be obtained from a portion of the respiratory health questionnaire. Comparison will be made between exposed and control counties and communities. Investigators also will conduct literature reviews of these toxic agents to identify their level of risk with respect to causing cancer in humans.
| Protocol I | Protocol II |
| Protocol III | Protocol IV |
| Protocol V | Protocol VI |
